KEGG   PATHWAY: bro00630
Entry
bro00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Bradyrhizobium sp. ORS 285
Class
Metabolism; Carbohydrate metabolism
Pathway map
bro00630  Glyoxylate and dicarboxylate metabolism
bro00630

Module
bro_M00012  Glyoxylate cycle [PATH:bro00630]
bro_M00621  Glycine cleavage system [PATH:bro00630]
bro_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bro00630]
Other DBs
GO: 0046487 0043648
Organism
Bradyrhizobium sp. ORS 285 [GN:bro]
Gene
BRAD285_3635  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BRAD285_7302  acsA; Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme) [KO:K01895] [EC:6.2.1.1]
BRAD285_0807  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BRAD285_2876  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BRAD285_0567  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
BRAD285_7240  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BRAD285_3249  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
BRAD285_0083  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
BRAD285_0084  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
BRAD285_7251  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BRAD285_2854  putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
BRAD285_2869  atoB; acetyl-CoA acetyltransferase with thiolase domain [KO:K00626] [EC:2.3.1.9]
BRAD285_0028  phbA; acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
BRAD285_4950  acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
BRAD285_0425  putative acetyl-CoA acetyltransferase with thiolase domain [KO:K00626] [EC:2.3.1.9]
BRAD285_0484  pimB; Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase) [KO:K00626] [EC:2.3.1.9]
BRAD285_6794  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
BRAD285_3090  putative thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BRAD285_4775  conserved protein of unknown function [KO:K00626] [EC:2.3.1.9]
BRAD285_0029  phbB; acetoacetyl-coA reductase [KO:K00023] [EC:1.1.1.36]
BRAD285_4076  Putative glyoxalase I family protein; putative Methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
BRAD285_3146  accA1; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase; Biotin carboxyl carrier protein] [KO:K01965] [EC:6.4.1.3]
BRAD285_3075  yqjD; propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BRAD285_4651  mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta) [KO:K01847] [EC:5.4.99.2]
BRAD285_4653  mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha) [KO:K01847] [EC:5.4.99.2]
BRAD285_6106  glcD; glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
BRAD285_6099  glcE; glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
BRAD285_6098  glcF; Glycolate oxidase subunit, (Fe-S)protein, GlcF [KO:K11473] [EC:1.1.99.14]
BRAD285_0880  putative catalase, homologous to the Protein srpA precursor [KO:K03781] [EC:1.11.1.6]
BRAD285_7604  putative D-isomer specific 2-hydroxyacid dehydrogenases family protein; Glyoxylate reductase (Glycolate reductase) [KO:K00015] [EC:1.1.1.26]
BRAD285_3925  ghrA; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BRAD285_0679  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BRAD285_3195  putative 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BRAD285_2539  cbbZ; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BRAD285_3371  putative phosphoglycolate phosphatase; putative Haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
BRAD285_7652  putative haloacid dehalogenase-like hydrolase family protein; putative Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BRAD285_5742  cbbL; Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit) [KO:K01601] [EC:4.1.1.39]
BRAD285_5741  cbbS; Ribulose bisphosphate carboxylase small chain (RuBisCO small subunit) [KO:K01602] [EC:4.1.1.39]
BRAD285_7126  putative Aminotransferase; Serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BRAD285_1956  Serine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BRAD285_1957  serine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BRAD285_6719  putative glutamine synthetase (glnA4-like) [KO:K01915] [EC:6.3.1.2]
BRAD285_3954  glnII; Glutamine synthetase II (Glutamate--ammonia ligase II) (GSII) (modular protein) [KO:K01915] [EC:6.3.1.2]
BRAD285_4113  glnA; Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI) [KO:K01915] [EC:6.3.1.2]
BRAD285_4187  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BRAD285_2261  gcvP; Glycine cleavage system P-protein (glycine dehydrogenase) [KO:K00281] [EC:1.4.4.2]
BRAD285_2263  gcvT; glycine cleavage system T-protein (aminomethyltransferase) [KO:K00605] [EC:2.1.2.10]
BRAD285_3295  lpD; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) [KO:K00382] [EC:1.8.1.4]
BRAD285_7233  lpd; dihydrolipoamide dehydrogenase, FAD/NAD(P)-binding, component of the 2-oxoglutarate dehydrogenase and the pyruvate dehydrogenase complexes [KO:K00382] [EC:1.8.1.4]
BRAD285_2262  gcvH; Glycine cleavage system H-protein [KO:K02437]
BRAD285_2302  gcl; Glyoxylate carboligase (Tartronate-semialdehyde synthase) [KO:K01608] [EC:4.1.1.47]
BRAD285_2303  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BRAD285_0471  Putative hydroxypyruvate reductase; Putative glycerate kinase [KO:K11529] [EC:2.7.1.165]
BRAD285_4815  yeaU; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BRAD285_2144  ttuC; Tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BRAD285_5479  eda; KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase, KHG-aldolase); 2-dehydro-3-deoxy-phosphogluconate aldolase (Phospho-2-dehydro-3-deoxygluconate aldolase, KDPG-aldolase)] [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BRAD285_0574  oxdD; Oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
BRAD285_2266  fdsD; putative formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
BRAD285_2268  fdsA; Formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BRAD285_2269  fdsB; putative formate dehydrogenase beta subunit [KO:K00124]
BRAD285_2270  fdsG; putative formate dehydrogenase gamma subunit [KO:K00127]
BRAD285_5870  putative hydrolase (Serine esterase) [KO:K01432] [EC:3.5.1.9]
BRAD285_1001  putative para-nitrobenzyl esterase [KO:K01432] [EC:3.5.1.9]
BRAD285_1978  purU; Formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase) [KO:K01433] [EC:3.5.1.10]
BRAD285_7717  amiF; Formamidase (Formamide amidohydrolase) [KO:K01455] [EC:3.5.1.49]
BRAD285_7028  fmdA; formamidase (formamide amidohydrolase) [KO:K01455] [EC:3.5.1.49]
BRAD285_2296  oxc; Oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
BRAD285_2295  frc; Formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bro00010  Glycolysis / Gluconeogenesis
bro00020  Citrate cycle (TCA cycle)
bro00030  Pentose phosphate pathway
bro00053  Ascorbate and aldarate metabolism
bro00071  Fatty acid degradation
bro00230  Purine metabolism
bro00250  Alanine, aspartate and glutamate metabolism
bro00260  Glycine, serine and threonine metabolism
bro00620  Pyruvate metabolism
bro00710  Carbon fixation by Calvin cycle
bro00750  Vitamin B6 metabolism
bro00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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