KEGG   PATHWAY: brw00620
Entry
brw00620                    Pathway                                
Name
Pyruvate metabolism - Brevibacillus sp. 7WMA2
Class
Metabolism; Carbohydrate metabolism
Pathway map
brw00620  Pyruvate metabolism
brw00620

Module
brw_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:brw00620]
brw_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:brw00620]
Other DBs
GO: 0006090
Organism
Brevibacillus sp. 7WMA2 [GN:brw]
Gene
GOP56_00260  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GOP56_06400  acyl--CoA ligase [KO:K01895] [EC:6.2.1.1]
GOP56_20985  pyruvate synthase [KO:K00169] [EC:1.2.7.1]
GOP56_20980  4Fe-4S dicluster domain-containing protein [KO:K00172] [EC:1.2.7.1]
GOP56_08170  2-oxoacid:acceptor oxidoreductase subunit alpha [KO:K00174] [EC:1.2.7.3 1.2.7.11]
GOP56_08165  2-oxoacid:ferredoxin oxidoreductase subunit beta [KO:K00175] [EC:1.2.7.3 1.2.7.11]
GOP56_07060  pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [KO:K00161] [EC:1.2.4.1]
GOP56_07055  alpha-ketoacid dehydrogenase subunit beta [KO:K00162] [EC:1.2.4.1]
GOP56_02395  2-oxo acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
GOP56_07050  2-oxo acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
GOP56_01715  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GOP56_02400  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GOP56_07045  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GOP56_21135  pflB; formate C-acetyltransferase [KO:K00656] [EC:2.3.1.54]
GOP56_05225  acetaldehyde dehydrogenase (acetylating) [KO:K00132] [EC:1.2.1.10]
GOP56_05915  acetaldehyde dehydrogenase (acetylating) [KO:K00132] [EC:1.2.1.10]
GOP56_13770  adhE; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [KO:K04072] [EC:1.2.1.10 1.1.1.1]
GOP56_13655  acetate/propionate family kinase [KO:K00925] [EC:2.7.2.1]
GOP56_19080  acetate kinase [KO:K00925] [EC:2.7.2.1]
GOP56_05215  phosphate propanoyltransferase [KO:K15024] [EC:2.3.1.8]
GOP56_05900  phosphate propanoyltransferase [KO:K15024] [EC:2.3.1.8]
GOP56_20535  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
GOP56_20525  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
GOP56_01290  accB; acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
GOP56_09635  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K02160]
GOP56_01295  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
GOP56_09640  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
GOP56_20520  acetyl-CoA carboxylase carboxyltransferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
GOP56_15125  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
GOP56_06495  aldehyde dehydrogenase family protein [KO:K00138] [EC:1.2.1.-]
GOP56_16005  L-lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
GOP56_20250  FAD-binding protein [KO:K00102] [EC:1.1.2.4]
GOP56_15655  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
GOP56_20905  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
GOP56_19025  aldo/keto reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
GOP56_03100  VOC family protein [KO:K01759] [EC:4.4.1.5]
GOP56_07675  VOC family protein [KO:K01759] [EC:4.4.1.5]
GOP56_09690  MBL fold metallo-hydrolase [KO:K01069] [EC:3.1.2.6]
GOP56_13210  MBL fold metallo-hydrolase [KO:K01069] [EC:3.1.2.6]
GOP56_20505  NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
GOP56_11895  pyc; pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
GOP56_20565  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GOP56_15685  malate:quinone oxidoreductase [KO:K00116] [EC:1.1.5.4]
GOP56_00365  fumarate hydratase [KO:K01676] [EC:4.2.1.2]
GOP56_13355  pckA; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
GOP56_16070  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
GOP56_21650  thiolase family protein [KO:K00626] [EC:2.3.1.9]
GOP56_14775  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GOP56_14935  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GOP56_21450  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
GOP56_12605  citramalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
brw00010  Glycolysis / Gluconeogenesis
brw00020  Citrate cycle (TCA cycle)
brw00061  Fatty acid biosynthesis
brw00250  Alanine, aspartate and glutamate metabolism
brw00260  Glycine, serine and threonine metabolism
brw00290  Valine, leucine and isoleucine biosynthesis
brw00300  Lysine biosynthesis
brw00630  Glyoxylate and dicarboxylate metabolism
brw00640  Propanoate metabolism
brw00650  Butanoate metabolism
brw00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   
LinkDB

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