KEGG   PATHWAY: bthe00630
Entry
bthe00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia thailandensis E254
Class
Metabolism; Carbohydrate metabolism
Pathway map
bthe00630  Glyoxylate and dicarboxylate metabolism
bthe00630

Module
bthe_M00012  Glyoxylate cycle [PATH:bthe00630]
bthe_M00621  Glycine cleavage system [PATH:bthe00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia thailandensis E254 [GN:bthe]
Gene
BTN_3085  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BTN_2256  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BTN_3384  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BTN_4213  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BTN_4420  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BTN_3089  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BTN_4467  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
BTN_5437  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BTN_4028  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BTN_1760  merR regulatory family protein [KO:K01647] [EC:2.3.3.1]
BTN_5444  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BTN_5433  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BTN_2830  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BTN_2835  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BTN_2943  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BTN_1357  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BTN_1085  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BTN_2834  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BTN_5243  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BTN_404  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BTN_405  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BTN_406  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BTN_1095  catalase family protein [KO:K03781] [EC:1.11.1.6]
BTN_1327  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BTN_2789  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BTN_16  NADP oxidoreductase coenzyme F420-dependent family protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BTN_7  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BTN_608  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BTN_3830  haloacid dehalogenase-like hydrolase family protein [KO:K01091] [EC:3.1.3.18]
BTN_3220  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BTN_3255  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BTN_4353  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BTN_317  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BTN_4277  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BTN_938  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BTN_940  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BTN_2539  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BTN_3198  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BTN_4711  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BTN_939  gcvH; glycine cleavage system H protein [KO:K02437]
BTN_2917  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BTN_2918  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BTN_2919  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BTN_2969  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BTN_4989  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BTN_4796  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BTN_477  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BTN_3495  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
BTN_93  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
BTN_92  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BTN_5485  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BTN_5484  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
BTN_91  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BTN_5486  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
BTN_90  respiratory-chain NADH dehydrogenase 24 Kd subunit [KO:K00127]
BTN_5487  formate dehydrogenase, gamma subunit [KO:K00127]
BTN_1719  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BTN_1508  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BTN_4266  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BTN_3257  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bthe00010  Glycolysis / Gluconeogenesis
bthe00020  Citrate cycle (TCA cycle)
bthe00030  Pentose phosphate pathway
bthe00053  Ascorbate and aldarate metabolism
bthe00071  Fatty acid degradation
bthe00230  Purine metabolism
bthe00250  Alanine, aspartate and glutamate metabolism
bthe00260  Glycine, serine and threonine metabolism
bthe00620  Pyruvate metabolism
bthe00710  Carbon fixation by Calvin cycle
bthe00750  Vitamin B6 metabolism
bthe00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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