KEGG   PATHWAY: bthe00230
Entry
bthe00230                   Pathway                                
Name
Purine metabolism - Burkholderia thailandensis E254
Class
Metabolism; Nucleotide metabolism
Pathway map
bthe00230  Purine metabolism
bthe00230

Module
bthe_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bthe00230]
bthe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bthe00230]
bthe_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bthe00230]
bthe_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bthe00230]
bthe_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bthe00230]
bthe_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bthe00230]
bthe_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bthe00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia thailandensis E254 [GN:bthe]
Gene
BTN_102  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BTN_1023  [KO:K01951] [EC:6.3.5.2]
BTN_104  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BTN_127  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BTN_129  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BTN_132  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BTN_1385  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BTN_1486  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BTN_1505  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BTN_1626  [KO:K01768] [EC:4.6.1.1]
BTN_1674  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BTN_1675  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BTN_1676  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BTN_1746  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BTN_1780  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BTN_1828  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BTN_1829  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BTN_1988  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BTN_2024  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BTN_2088  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BTN_216  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BTN_217  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BTN_2173  [KO:K03651] [EC:3.1.4.53]
BTN_218  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BTN_2244  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BTN_225  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BTN_246  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BTN_2501  [KO:K00951] [EC:2.7.6.5]
BTN_2702  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
BTN_2837  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BTN_2846  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BTN_286  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BTN_2860  [KO:K00940] [EC:2.7.4.6]
BTN_2868  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BTN_287  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BTN_2952  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BTN_3010  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BTN_3015  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BTN_3016  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BTN_3017  [KO:K16842] [EC:3.5.2.5]
BTN_3018  [KO:K16841] [EC:5.1.99.3]
BTN_3025  guaA; GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
BTN_3027  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BTN_3115  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BTN_3131  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTN_3267  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTN_3274  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BTN_3374  prs; ribose-phosphate diphosphokinase family protein [KO:K00948] [EC:2.7.6.1]
BTN_379  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BTN_4343  [KO:K00525] [EC:1.17.4.1]
BTN_4410  [KO:K01939] [EC:6.3.4.4]
BTN_445  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BTN_4610  [KO:K16856] [EC:4.3.2.3]
BTN_4725  [KO:K00525] [EC:1.17.4.1]
BTN_474  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BTN_490  [KO:K01483] [EC:4.3.2.3]
BTN_491  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BTN_5232  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTN_534  [KO:K00856] [EC:2.7.1.20]
BTN_537  [KO:K00526] [EC:1.17.4.1]
BTN_538  [KO:K00525] [EC:1.17.4.1]
BTN_5384  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BTN_543  [KO:K00760] [EC:2.4.2.8]
BTN_5465  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BTN_726  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bthe00030  Pentose phosphate pathway
bthe00220  Arginine biosynthesis
bthe00250  Alanine, aspartate and glutamate metabolism
bthe00260  Glycine, serine and threonine metabolism
bthe00340  Histidine metabolism
bthe00630  Glyoxylate and dicarboxylate metabolism
bthe00730  Thiamine metabolism
bthe00740  Riboflavin metabolism
bthe00790  Folate biosynthesis
KO pathway
ko00230   

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