Entry |
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Name |
Glutathione metabolism - Crocosphaera subtropica |
Class |
Metabolism; Metabolism of other amino acids
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Pathway map |
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Other DBs |
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Organism |
Crocosphaera subtropica [GN: cyt]
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Gene |
cce_1175 | Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) family [KO:K00799] [EC:2.5.1.18] |
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Compound |
C00669 | gamma-L-Glutamyl-L-cysteine |
C03170 | Trypanothione disulfide |
C03646 | Bis-gamma-glutamylcystine |
C03740 | (5-L-Glutamyl)-L-amino acid |
C05726 | S-Substituted L-cysteine |
C05727 | S-Substituted N-acetyl-L-cysteine |
C16563 | Bis(glutathionyl)spermine |
C16564 | Bis(glutathionyl)spermine disulfide |
C16566 | Glutathionylaminopropylcadaverine |
C16568 | Homotrypanothione disulfide |
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Reference |
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Authors |
Josch C, Klotz LO, Sies H. |
Title |
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver. |
Journal |
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Reference |
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Authors |
Chu L, Lai Y, Xu X, Eddy S, Yang S, Song L, Kolodrubetz D. |
Title |
A 52-kDa leucyl aminopeptidase from treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism. |
Journal |
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Reference |
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Authors |
Cappiello M, Lazzarotti A, Buono F, Scaloni A, D'Ambrosio C, Amodeo P, Mendez BL, Pelosi P, Del Corso A, Mura U. |
Title |
New role for leucyl aminopeptidase in glutathione turnover. |
Journal |
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Reference |
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Authors |
Suzuki H, Kamatani S, Kim ES, Kumagai H. |
Title |
Aminopeptidases A, B, and N and dipeptidase D are the four cysteinylglycinases of Escherichia coli K-12. |
Journal |
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Reference |
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Authors |
Oza SL, Shaw MP, Wyllie S, Fairlamb AH. |
Title |
Trypanothione biosynthesis in Leishmania major. |
Journal |
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Reference |
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Authors |
Oza SL, Ariyanayagam MR, Fairlamb AH. |
Title |
Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata. |
Journal |
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Reference |
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Authors |
Tetaud E, Manai F, Barrett MP, Nadeau K, Walsh CT, Fairlamb AH. |
Title |
Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata. |
Journal |
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Reference |
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Authors |
Ariyanayagam MR, Oza SL, Mehlert A, Fairlamb AH. |
Title |
Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi. |
Journal |
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Reference |
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Authors |
Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH. |
Title |
Properties of trypanothione synthetase from Trypanosoma brucei. |
Journal |
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Reference |
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Authors |
Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH. |
Title |
A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi. |
Journal |
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Reference |
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Authors |
Comini M, Menge U, Wissing J, Flohe L. |
Title |
Trypanothione synthesis in crithidia revisited. |
Journal |
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Reference |
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Authors |
Hunter KJ, Le Quesne SA, Fairlamb AH. |
Title |
Identification and biosynthesis of N1,N9-bis(glutathionyl)aminopropylcadaverine (homotrypanothione) in Trypanosoma cruzi. |
Journal |
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Reference |
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Authors |
Krauth-Siegel RL, Meiering SK, Schmidt H. |
Title |
The parasite-specific trypanothione metabolism of trypanosoma and leishmania. |
Journal |
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Reference |
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Authors |
Krauth-Siegel RL, Comini MA. |
Title |
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism. |
Journal |
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Reference |
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Authors |
Krauth-Siegel RL, Ludemann H. |
Title |
Reduction of dehydroascorbate by trypanothione. |
Journal |
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Reference |
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Authors |
Dormeyer M, Reckenfelderbaumer N, Ludemann H, Krauth-Siegel RL. |
Title |
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase. |
Journal |
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Reference |
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Authors |
Schmidt H, Krauth-Siegel RL. |
Title |
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei. |
Journal |
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Reference |
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Authors |
Tetaud E, Fairlamb AH. |
Title |
Cloning, expression and reconstitution of the trypanothione-dependent peroxidase system of Crithidia fasciculata. |
Journal |
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Reference |
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Authors |
Castro H, Sousa C, Santos M, Cordeiro-da-Silva A, Flohe L, Tomas AM. |
Title |
Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum. |
Journal |
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Reference |
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Authors |
Wilkinson SR, Temperton NJ, Mondragon A, Kelly JM. |
Title |
Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi. |
Journal |
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Reference |
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Authors |
Konig J, Fairlamb AH. |
Title |
A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major. |
Journal |
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Reference |
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Authors |
Hillebrand H, Schmidt A, Krauth-Siegel RL. |
Title |
A second class of peroxidases linked to the trypanothione metabolism. |
Journal |
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Reference |
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Authors |
Soksawatmaekhin W, Kuraishi A, Sakata K, Kashiwagi K, Igarashi K. |
Title |
Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli. |
Journal |
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Reference |
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Authors |
Pegg AE, Shuttleworth K, Hibasami H. |
Title |
Specificity of mammalian spermidine synthase and spermine synthase. |
Journal |
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Related pathway |
cyt00250 | Alanine, aspartate and glutamate metabolism |
cyt00270 | Cysteine and methionine metabolism |
cyt00430 | Taurine and hypotaurine metabolism |
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KO pathway |
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LinkDB |
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