KEGG   PATHWAY: efo00630
Entry
efo00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Epinephelus fuscoguttatus (brown-marbled grouper)
Class
Metabolism; Carbohydrate metabolism
Pathway map
efo00630  Glyoxylate and dicarboxylate metabolism
efo00630

Module
efo_M00621  Glycine cleavage system [PATH:efo00630]
efo_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:efo00630]
Other DBs
GO: 0046487 0043648
Organism
Epinephelus fuscoguttatus (brown-marbled grouper) [GN:efo]
Gene
125901948  acss2l; acyl-CoA synthetase short chain family member 2 like [KO:K01895] [EC:6.2.1.1]
125896701  acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
125903262  acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1 [KO:K01895] [EC:6.2.1.1]
125891277  acss2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
125903213  mdh1ab; malate dehydrogenase 1Ab, NAD (soluble) [KO:K00025] [EC:1.1.1.37]
125886379  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
125892830  mdh2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
125891368  cs; citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
125884062  aco1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
125878932  aconitate hydratase, mitochondrial-like [KO:K01681] [EC:4.2.1.3]
125880335  aco2; aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
125896912  acat2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
125897985  acat1; acetyl-CoA acetyltransferase, mitochondrial isoform X1 [KO:K00626] [EC:2.3.1.9]
125900768  mcee; methylmalonyl-CoA epimerase, mitochondrial [KO:K05606] [EC:5.1.99.1]
125903961  pcca; propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
125900615  pccb; propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
125897068  mmut; methylmalonyl-CoA mutase, mitochondrial [KO:K01847] [EC:5.4.99.2]
125878847  hao1; hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
125900204  hao2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
125887057  cat; catalase [KO:K03781] [EC:1.11.1.6]
125886468  grhprb; glyoxylate reductase/hydroxypyruvate reductase b [KO:K00049] [EC:1.1.1.79 1.1.1.81]
125894835  grhpra; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
125880275  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
125896313  agxta; alanine--glyoxylate and serine--pyruvate aminotransferase a [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
125902464  agxtb; alanine--glyoxylate and serine--pyruvate aminotransferase b [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
125896063  glulb; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
125902120  glula; glutamate-ammonia ligase (glutamine synthase) a [KO:K01915] [EC:6.3.1.2]
125906257  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
125895395  shmt2; serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
125891958  serine hydroxymethyltransferase, mitochondrial-like [KO:K00600] [EC:2.1.2.1]
125879244  shmt1; serine hydroxymethyltransferase, cytosolic [KO:K00600] [EC:2.1.2.1]
125890031  gldc; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
125891127  amt; aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
125887801  dldh; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
125902878  gcshb; glycine cleavage system protein H (aminomethyl carrier), b [KO:K02437]
125887224  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
125895896  hyi; putative hydroxypyruvate isomerase isoform X1 [KO:K01816] [EC:5.3.1.22]
125886420  glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
125885368  hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
125886032  afmid; kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
efo00010  Glycolysis / Gluconeogenesis
efo00020  Citrate cycle (TCA cycle)
efo00030  Pentose phosphate pathway
efo00053  Ascorbate and aldarate metabolism
efo00071  Fatty acid degradation
efo00230  Purine metabolism
efo00250  Alanine, aspartate and glutamate metabolism
efo00260  Glycine, serine and threonine metabolism
efo00620  Pyruvate metabolism
efo00750  Vitamin B6 metabolism
efo00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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