KEGG   PATHWAY: gai00061
Entry
gai00061                    Pathway                                
Name
Fatty acid biosynthesis - Granulosicoccus antarcticus
Class
Metabolism; Lipid metabolism
Pathway map
gai00061  Fatty acid biosynthesis
gai00061

Module
gai_M00082  Fatty acid biosynthesis, initiation [PATH:gai00061]
gai_M00083  Fatty acid biosynthesis, elongation [PATH:gai00061]
gai_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:gai00061]
Other DBs
GO: 0006633
Organism
Granulosicoccus antarcticus [GN:gai]
Gene
IMCC3135_23820  accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
IMCC3135_06580  accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase [KO:K02160]
IMCC3135_06585  accC; Biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
IMCC3135_26380  accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
IMCC3135_24015  fabD; Malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
IMCC3135_21835  fabH_1; 3-oxoacyl-[acyl-carrier-protein] synthase 3 [KO:K00648] [EC:2.3.1.180]
IMCC3135_13390  fabH2; 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 [KO:K00648] [EC:2.3.1.180]
IMCC3135_06555  fabB_1; 3-oxoacyl-[acyl-carrier-protein] synthase 1 [KO:K00647] [EC:2.3.1.41]
IMCC3135_13420  fabF_1; 3-oxoacyl-[acyl-carrier-protein] synthase 2 [KO:K00647] [EC:2.3.1.41]
IMCC3135_33790  hypothetical protein [KO:K00647] [EC:2.3.1.41]
IMCC3135_34095  fabF_3; 3-oxoacyl-[acyl-carrier-protein] synthase 2 [KO:K00647] [EC:2.3.1.41]
IMCC3135_24000  fabF_2; 3-oxoacyl-[acyl-carrier-protein] synthase 2 [KO:K09458] [EC:2.3.1.179]
IMCC3135_34110  fabB_2; 3-oxoacyl-[acyl-carrier-protein] synthase 1 [KO:K09458] [EC:2.3.1.179]
IMCC3135_09805  ped_1; (S)-1-Phenylethanol dehydrogenase [KO:K00059] [EC:1.1.1.100]
IMCC3135_10815  fabG1_1; 3-oxoacyl-[acyl-carrier-protein] reductase 1 [KO:K00059] [EC:1.1.1.100]
IMCC3135_04650  tsaC1_1; 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 [KO:K00059] [EC:1.1.1.100]
IMCC3135_06930  fabG_1; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00059] [EC:1.1.1.100]
IMCC3135_21370  ywfH; Bacilysin biosynthesis oxidoreductase YwfH [KO:K00059] [EC:1.1.1.100]
IMCC3135_14105  fabG_2; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00059] [EC:1.1.1.100]
IMCC3135_24010  fabG_7; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00059] [EC:1.1.1.100]
IMCC3135_34105  fabG_8; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00059] [EC:1.1.1.100]
IMCC3135_13355  fabG2; 3-oxoacyl-[acyl-carrier-protein] reductase 2 [KO:K00059] [EC:1.1.1.100]
IMCC3135_06550  fabA; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [KO:K01716] [EC:4.2.1.59 5.3.3.14]
IMCC3135_25475  fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
IMCC3135_23485  fabI_1; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
IMCC3135_25550  fabI_2; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI [KO:K00208] [EC:1.3.1.9 1.3.1.10]
IMCC3135_03540  yhfT; putative acyl--CoA ligase YhfT [KO:K01897] [EC:6.2.1.3]
IMCC3135_22020  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
IMCC3135_24465  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
IMCC3135_33195  fadD; Long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
IMCC3135_16820  lcfB_3; Long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
gai00020  Citrate cycle (TCA cycle)
gai00071  Fatty acid degradation
gai00410  beta-Alanine metabolism
gai00561  Glycerolipid metabolism
gai00564  Glycerophospholipid metabolism
gai00620  Pyruvate metabolism
gai00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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