KEGG   PATHWAY: gep00630
Entry
gep00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Geothrix sp. PMB-07
Class
Metabolism; Carbohydrate metabolism
Pathway map
gep00630  Glyoxylate and dicarboxylate metabolism
gep00630

Module
gep_M00012  Glyoxylate cycle [PATH:gep00630]
gep_M00621  Glycine cleavage system [PATH:gep00630]
Other DBs
GO: 0046487 0043648
Organism
Geothrix sp. PMB-07 [GN:gep]
Gene
Q9293_16695  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Q9293_04625  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Q9293_17265  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Q9293_12535  hypothetical protein [KO:K01638] [EC:2.3.3.9]
Q9293_09600  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Q9293_02240  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
Q9293_04560  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Q9293_07345  thiolase family protein [KO:K00626] [EC:2.3.1.9]
Q9293_10490  thiolase family protein [KO:K00626] [EC:2.3.1.9]
Q9293_15675  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Q9293_15235  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Q9293_00205  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Q9293_10805  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
Q9293_10395  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Q9293_01705  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
Q9293_03255  hydroxyacid dehydrogenase [KO:K22982] [EC:1.1.1.81]
Q9293_03720  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
Q9293_06805  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
Q9293_14620  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
Q9293_17240  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
Q9293_09510  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
Q9293_05685  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
Q9293_13925  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
Q9293_17465  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
Q9293_00020  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Q9293_00635  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
Q9293_18085  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
Q9293_00640  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
Q9293_18090  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
Q9293_08810  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
Q9293_17220  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Q9293_08815  gcvH; glycine cleavage system protein GcvH [KO:K02437]
Q9293_12540  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Q9293_18465  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Q9293_06010  4Fe-4S dicluster domain-containing protein [KO:K00124]
Q9293_15670  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
gep00010  Glycolysis / Gluconeogenesis
gep00020  Citrate cycle (TCA cycle)
gep00030  Pentose phosphate pathway
gep00053  Ascorbate and aldarate metabolism
gep00071  Fatty acid degradation
gep00230  Purine metabolism
gep00250  Alanine, aspartate and glutamate metabolism
gep00260  Glycine, serine and threonine metabolism
gep00620  Pyruvate metabolism
gep00710  Carbon fixation by Calvin cycle
gep00750  Vitamin B6 metabolism
gep00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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