KEGG   PATHWAY: halg00630
Entry
halg00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halobaculum halophilum
Class
Metabolism; Carbohydrate metabolism
Pathway map
halg00630  Glyoxylate and dicarboxylate metabolism
halg00630

Module
halg_M00012  Glyoxylate cycle [PATH:halg00630]
halg_M00621  Glycine cleavage system [PATH:halg00630]
halg_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:halg00630]
halg_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:halg00630]
Other DBs
GO: 0046487 0043648
Organism
Halobaculum halophilum [GN:halg]
Gene
HUG10_17635  isocitrate lyase/PEP mutase family protein [KO:K01637] [EC:4.1.3.1]
HUG10_05370  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
HUG10_08305  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
HUG10_14115  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
HUG10_13200  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HUG10_15135  lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
HUG10_17080  citrate synthase [KO:K01647] [EC:2.3.3.1]
HUG10_04070  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
HUG10_10680  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
HUG10_18560  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
HUG10_00115  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
HUG10_03520  thiolase family protein [KO:K00626] [EC:2.3.1.9]
HUG10_08745  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
HUG10_12540  thiolase family protein [KO:K00626] [EC:2.3.1.9]
HUG10_19365  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
HUG10_06385  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
HUG10_03110  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
HUG10_03100  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
HUG10_03105  acc operon protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
HUG10_00095  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
HUG10_06350  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
HUG10_14110  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
HUG10_03375  malate synthase [KO:K19282] [EC:4.1.3.24 3.1.2.30]
HUG10_03295  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
HUG10_09290  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
HUG10_06655  HAD hydrolase family protein [KO:K22223] [EC:3.1.3.18]
HUG10_04680  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
HUG10_00530  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
HUG10_13610  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
HUG10_03615  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
HUG10_17615  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
HUG10_17620  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
HUG10_16805  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
HUG10_17595  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
HUG10_12640  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HUG10_15105  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
HUG10_17605  gcvH; glycine cleavage system protein GcvH [KO:K02437]
HUG10_09665  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
HUG10_06710  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
HUG10_05570  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
HUG10_17300  HAD family hydrolase [KO:K26210] [EC:3.1.3.109]
HUG10_17305  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
HUG10_06815  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
HUG10_06825  isocitrate/isopropylmalate dehydrogenase family protein [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
HUG10_08500  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
HUG10_09445  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
HUG10_09440  4Fe-4S dicluster domain-containing protein [KO:K00124]
HUG10_09375  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
halg00010  Glycolysis / Gluconeogenesis
halg00020  Citrate cycle (TCA cycle)
halg00030  Pentose phosphate pathway
halg00053  Ascorbate and aldarate metabolism
halg00071  Fatty acid degradation
halg00230  Purine metabolism
halg00250  Alanine, aspartate and glutamate metabolism
halg00260  Glycine, serine and threonine metabolism
halg00620  Pyruvate metabolism
halg00710  Carbon fixation by Calvin cycle
halg00750  Vitamin B6 metabolism
halg00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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