KEGG   PATHWAY: han00061
Entry
han00061                    Pathway                                
Name
Fatty acid biosynthesis - Helianthus annuus (common sunflower)
Class
Metabolism; Lipid metabolism
Pathway map
han00061  Fatty acid biosynthesis
han00061

Module
han_M00082  Fatty acid biosynthesis, initiation [PATH:han00061]
han_M00083  Fatty acid biosynthesis, elongation [PATH:han00061]
han_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:han00061]
Other DBs
GO: 0006633
Organism
Helianthus annuus (common sunflower) [GN:han]
Gene
110889119  acetyl-CoA carboxylase 1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
110941075  acetyl-CoA carboxylase 1 isoform X1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
110909894  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
110884807  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
110884458  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
110879644  biotin carboxyl carrier protein of acetyl-CoA carboxylase, chloroplastic [KO:K02160]
110917264  biotin carboxyl carrier protein of acetyl-CoA carboxylase 2, chloroplastic [KO:K02160]
110915869  biotin carboxyl carrier protein of acetyl-CoA carboxylase, chloroplastic [KO:K02160]
110941901  biotin carboxyl carrier protein of acetyl-CoA carboxylase, chloroplastic isoform X2 [KO:K02160]
110920936  biotin carboxylase 2, chloroplastic [KO:K01961] [EC:6.4.1.2 6.3.4.14]
110882513  biotin carboxylase 2, chloroplastic [KO:K01961] [EC:6.4.1.2 6.3.4.14]
4055710  accD; acetyl-CoA carboxylase beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
118484082  acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [KO:K01963] [EC:6.4.1.2 2.1.3.15]
110918791  malonate--CoA ligase isoform X1 [KO:K18660] [EC:6.2.1.76 6.2.1.-]
110869205  malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
110911012  malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
110922783  3-oxoacyl-[acyl-carrier-protein] synthase 3 B, chloroplastic [KO:K00648] [EC:2.3.1.180]
110921619  3-oxoacyl-[acyl-carrier-protein] synthase III, chloroplastic isoform X1 [KO:K00648] [EC:2.3.1.180]
110865447  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic isoform X1 [KO:K09458] [EC:2.3.1.179]
110899519  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110869586  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
110918696  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial [KO:K09458] [EC:2.3.1.179]
110876113  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110875874  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110877021  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic [KO:K09458] [EC:2.3.1.179]
110913067  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic [KO:K09458] [EC:2.3.1.179]
110923177  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110925958  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110937383  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
110886898  3-oxoacyl-[acyl-carrier-protein] reductase 4 [KO:K00059] [EC:1.1.1.100]
110926202  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
110926207  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
110926295  3-oxoacyl-[acyl-carrier-protein] reductase 4 [KO:K00059] [EC:1.1.1.100]
110898165  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
110885197  3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
110928978  3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [KO:K02372] [EC:4.2.1.59]
110918310  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
110920857  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
110927155  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic [KO:K00208] [EC:1.3.1.9 1.3.1.10]
110865218  enoyl-[acyl-carrier-protein] reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
110939958  enoyl-[acyl-carrier-protein] reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
118479250  enoyl-[acyl-carrier-protein] reductase, mitochondrial-like [KO:K07512] [EC:1.3.1.- 1.3.1.38]
110865595  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110940305  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110877217  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110883188  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110883191  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110886372  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110886373  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110886378  palmitoyl-acyl carrier protein thioesterase, chloroplastic isoform X1 [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110886379  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
110871748  oleoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10782] [EC:3.1.2.14]
110890752  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
110878160  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
110867977  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
110867086  long chain acyl-CoA synthetase 7, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
110895747  long chain acyl-CoA synthetase 7, peroxisomal [KO:K01897] [EC:6.2.1.3]
110886089  long chain acyl-CoA synthetase 2 [KO:K01897] [EC:6.2.1.3]
110889498  long chain acyl-CoA synthetase 9, chloroplastic isoform X2 [KO:K01897] [EC:6.2.1.3]
110910053  long chain acyl-CoA synthetase 1 [KO:K01897] [EC:6.2.1.3]
110899498  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
110899500  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
110885243  long chain acyl-CoA synthetase 6, peroxisomal [KO:K01897] [EC:6.2.1.3]
110877298  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
110931053  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
110878808  long chain acyl-CoA synthetase 9, chloroplastic [KO:K01897] [EC:6.2.1.3]
110930246  long chain acyl-CoA synthetase 4 [KO:K01897] [EC:6.2.1.3]
110929342  long chain acyl-CoA synthetase 7, peroxisomal [KO:K01897] [EC:6.2.1.3]
110936374  long chain acyl-CoA synthetase 1 [KO:K01897] [EC:6.2.1.3]
110938092  long chain acyl-CoA synthetase 8 [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
han00020  Citrate cycle (TCA cycle)
han00062  Fatty acid elongation
han00071  Fatty acid degradation
han00410  beta-Alanine metabolism
han00561  Glycerolipid metabolism
han00564  Glycerophospholipid metabolism
han00620  Pyruvate metabolism
han00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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