KEGG   PATHWAY: hhb00630
Entry
hhb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halobacterium hubeiense
Class
Metabolism; Carbohydrate metabolism
Pathway map
hhb00630  Glyoxylate and dicarboxylate metabolism
hhb00630

Module
hhb_M00012  Glyoxylate cycle [PATH:hhb00630]
hhb_M00621  Glycine cleavage system [PATH:hhb00630]
hhb_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hhb00630]
hhb_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hhb00630]
Other DBs
GO: 0046487 0043648
Organism
Halobacterium hubeiense [GN:hhb]
Gene
Hhub_3379  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Hhub_1518  acs1; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Hhub_4035  acs6; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Hhub_2456  acs2; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Hhub_2458  acs8; acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Hhub_3725  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Hhub_3393  citZ; citrate synthase [KO:K01647] [EC:2.3.3.1]
Hhub_1094  citB1; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Hhub_6032  citB2; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Hhub_1504  acaB1; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Hhub_4061  acaB4; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Hhub_2111  acaB3; acetyl-CoA C-acetyltransferase catalytic subunit [KO:K00626] [EC:2.3.1.9]
Hhub_1525  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Hhub_2879  pccA; propionyl-CoA carboxylase biotin carboxylase component [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Hhub_2881  pccB1; propionyl-CoA carboxylase carboxyltransferase component [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Hhub_2880  uncharacterized protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
Hhub_1500  mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) [KO:K01849] [EC:5.4.99.2]
Hhub_1523  mmcA2; methylmalonyl-CoA mutase subunit A [KO:K01848] [EC:5.4.99.2]
Hhub_1656  mmcA1; methylmalonyl-CoA mutase subunit A [KO:K01848] [EC:5.4.99.2]
Hhub_3380  aceB; malate synthase [KO:K19282] [EC:4.1.3.24 3.1.2.30]
Hhub_2813  HAD superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
Hhub_3083  HAD superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
Hhub_1934  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
Hhub_2839  aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Hhub_1568  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
Hhub_3384  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Hhub_2666  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Hhub_2931  gcvP1; glycine cleavage system protein P alpha subunit [KO:K00282] [EC:1.4.4.2]
Hhub_2930  gcvP2; glycine cleavage system protein P beta subunit [KO:K00283] [EC:1.4.4.2]
Hhub_1275  homolog to glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
Hhub_2934  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
Hhub_1016  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Hhub_2933  gcvH; glycine cleavage system protein H [KO:K02437]
Hhub_2107  DUF4147 domain protein [KO:K11529] [EC:2.7.1.165]
Hhub_2472  HAD superfamily hydrolase [KO:K26210] [EC:3.1.3.109]
Hhub_2471  class II aldolase (homolog to L-fuculose-phosphate aldolase) [KO:K01636] [EC:4.1.2.-]
Hhub_4295  leuB2; 3-isopropylmalate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Hhub_1885  probable anaerobic dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
Hhub_1884  probable anaerobic dehydrogenase iron-sulfur-binding subunit [KO:K00124]
Hhub_3272  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Hhub_4239  probable acetamidase/formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hhb00010  Glycolysis / Gluconeogenesis
hhb00020  Citrate cycle (TCA cycle)
hhb00030  Pentose phosphate pathway
hhb00053  Ascorbate and aldarate metabolism
hhb00071  Fatty acid degradation
hhb00230  Purine metabolism
hhb00250  Alanine, aspartate and glutamate metabolism
hhb00260  Glycine, serine and threonine metabolism
hhb00620  Pyruvate metabolism
hhb00710  Carbon fixation by Calvin cycle
hhb00750  Vitamin B6 metabolism
hhb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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