KEGG   PATHWAY: hlu00630
Entry
hlu00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halobacterium litoreum
Class
Metabolism; Carbohydrate metabolism
Pathway map
hlu00630  Glyoxylate and dicarboxylate metabolism
hlu00630

Module
hlu_M00012  Glyoxylate cycle [PATH:hlu00630]
hlu_M00621  Glycine cleavage system [PATH:hlu00630]
hlu_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hlu00630]
hlu_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hlu00630]
Other DBs
GO: 0046487 0043648
Organism
Halobacterium litoreum [GN:hlu]
Gene
LT972_01035  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
LT972_09350  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LT972_10385  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LT972_12220  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LT972_07295  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LT972_07305  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LT972_14560  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LT972_00965  citrate synthase [KO:K01647] [EC:2.3.3.1]
LT972_04220  citrate synthase [KO:K01647] [EC:2.3.3.1]
LT972_13035  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
LT972_07730  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LT972_08930  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
LT972_04880  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LT972_09240  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
LT972_05915  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
LT972_10420  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
LT972_12140  VOC family protein [KO:K05606] [EC:5.1.99.1]
LT972_03630  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
LT972_03620  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
LT972_03625  acc operon protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
LT972_09260  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
LT972_09360  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
LT972_10410  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
LT972_01030  aldolase/citrate lyase family protein [KO:K19282] [EC:4.1.3.24 3.1.2.30]
LT972_02645  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
LT972_03990  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
LT972_08795  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
LT972_09175  rbcL; type III ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
LT972_03840  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
LT972_10785  gltB; glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
LT972_01010  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LT972_04180  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LT972_03520  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
LT972_03525  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
LT972_12655  aminomethyltransferase family protein [KO:K00605] [EC:2.1.2.10]
LT972_03510  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
LT972_12110  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LT972_13445  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LT972_03515  gcvH; glycine cleavage system protein GcvH [KO:K02437]
LT972_00865  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
LT972_08990  HAD family hydrolase [KO:K26210] [EC:3.1.3.109]
LT972_08995  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
LT972_01660  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hlu00010  Glycolysis / Gluconeogenesis
hlu00020  Citrate cycle (TCA cycle)
hlu00030  Pentose phosphate pathway
hlu00053  Ascorbate and aldarate metabolism
hlu00071  Fatty acid degradation
hlu00230  Purine metabolism
hlu00250  Alanine, aspartate and glutamate metabolism
hlu00260  Glycine, serine and threonine metabolism
hlu00620  Pyruvate metabolism
hlu00710  Carbon fixation by Calvin cycle
hlu00750  Vitamin B6 metabolism
hlu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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