KEGG   PATHWAY: kpa00630
Entry
kpa00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella pneumoniae 30660/NJST258_1
Class
Metabolism; Carbohydrate metabolism
Pathway map
kpa00630  Glyoxylate and dicarboxylate metabolism
kpa00630

Module
kpa_M00012  Glyoxylate cycle [PATH:kpa00630]
kpa_M00621  Glycine cleavage system [PATH:kpa00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella pneumoniae 30660/NJST258_1 [GN:kpa]
Gene
KPNJ1_05197  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KPNJ1_05198  Malate synthase [KO:K01638] [EC:2.3.3.9]
KPNJ1_00515  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
KPNJ1_04125  Citrate synthase [KO:K01647] [EC:2.3.3.1]
KPNJ1_03853  Citrate synthase [KO:K01647] [EC:2.3.3.1]
KPNJ1_03228  Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
KPNJ1_04605  Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KPNJ1_00974  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPNJ1_02415  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPNJ1_02792  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPNJ1_03272  Catalase HPII [KO:K03781] [EC:1.11.1.6]
KPNJ1_03471  hypothetical protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPNJ1_01269  D-3-phosphoglycerate dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPNJ1_00209  Gluconate 2-dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KPNJ1_00380  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KPNJ1_05424  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
KPNJ1_01405  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KPNJ1_00897  Glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
KPNJ1_00895  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
KPNJ1_04611  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPNJ1_04452  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPNJ1_00896  Glycine cleavage system H protein [KO:K02437]
KPNJ1_00616  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
KPNJ1_00617  2-phosphoglycerate kinase [KO:K00865] [EC:2.7.1.165]
KPNJ1_01110  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
KPNJ1_02797  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
KPNJ1_03249  Glycerate dehydrogenase [KO:K11529] [EC:2.7.1.165]
KPNJ1_02992  Aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KPNJ1_01082  Lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
KPNJ1_03514  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPNJ1_03250  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPNJ1_02057  4-Hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KPNJ1_05410  Formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
KPNJ1_05411  Formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
KPNJ1_05412  Formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
KPNJ1_05413  Formate dehydrogenase, cytochrome B556 subunit [KO:K00127]
KPNJ1_02240  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kpa00010  Glycolysis / Gluconeogenesis
kpa00020  Citrate cycle (TCA cycle)
kpa00030  Pentose phosphate pathway
kpa00053  Ascorbate and aldarate metabolism
kpa00071  Fatty acid degradation
kpa00230  Purine metabolism
kpa00250  Alanine, aspartate and glutamate metabolism
kpa00260  Glycine, serine and threonine metabolism
kpa00620  Pyruvate metabolism
kpa00710  Carbon fixation by Calvin cycle
kpa00750  Vitamin B6 metabolism
kpa00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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