KEGG   PATHWAY: kpo00630
Entry
kpo00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella pneumoniae KCTC 2242
Class
Metabolism; Carbohydrate metabolism
Pathway map
kpo00630  Glyoxylate and dicarboxylate metabolism
kpo00630

Module
kpo_M00012  Glyoxylate cycle [PATH:kpo00630]
kpo_M00621  Glycine cleavage system [PATH:kpo00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella pneumoniae KCTC 2242 [GN:kpo]
Gene
KPN2242_00020  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KPN2242_00445  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
KPN2242_00015  malate synthase [KO:K01638] [EC:2.3.3.9]
KPN2242_21250  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
KPN2242_05220  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
KPN2242_06485  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
KPN2242_09490  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
KPN2242_03060  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KPN2242_13230  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPN2242_11375  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPN2242_16290  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
KPN2242_19295  putative acyltransferase [KO:K00626] [EC:2.3.1.9]
KPN2242_09300  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
KPN2242_08345  ghrA; bifunctional glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPN2242_17875  2-ketoacid reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPN2242_22600  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KPN2242_21795  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KPN2242_23925  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
KPN2242_17450  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KPN2242_19825  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
KPN2242_19835  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
KPN2242_03040  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPN2242_03735  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
KPN2242_19830  glycine cleavage system protein H [KO:K02437]
KPN2242_20830  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
KPN2242_18665  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
KPN2242_20825  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
KPN2242_11355  glycerate kinase I [KO:K00865] [EC:2.7.1.165]
KPN2242_10290  aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KPN2242_18785  L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
KPN2242_08135  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPN2242_14805  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KPN2242_23985  formate dehydrogenase-O alpha subunit [KO:K00123] [EC:1.17.1.9]
KPN2242_23990  formate dehydrogenase-O alpha subunit [KO:K00123] [EC:1.17.1.9]
KPN2242_23980  formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
KPN2242_23975  formate dehydrogenase-O subunit gamma [KO:K00127]
KPN2242_14050  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kpo00010  Glycolysis / Gluconeogenesis
kpo00020  Citrate cycle (TCA cycle)
kpo00030  Pentose phosphate pathway
kpo00053  Ascorbate and aldarate metabolism
kpo00071  Fatty acid degradation
kpo00230  Purine metabolism
kpo00250  Alanine, aspartate and glutamate metabolism
kpo00260  Glycine, serine and threonine metabolism
kpo00620  Pyruvate metabolism
kpo00710  Carbon fixation by Calvin cycle
kpo00750  Vitamin B6 metabolism
kpo00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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