KEGG   PATHWAY: kpr00630
Entry
kpr00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
Class
Metabolism; Carbohydrate metabolism
Pathway map
kpr00630  Glyoxylate and dicarboxylate metabolism
kpr00630

Module
kpr_M00012  Glyoxylate cycle [PATH:kpr00630]
kpr_M00621  Glycine cleavage system [PATH:kpr00630]
Other DBs
GO: 0046487 0043648
Organism
Klebsiella pneumoniae subsp. rhinoscleromatis SB3432 [GN:kpr]
Gene
KPR_0377  aceA; highly similar to Isocitrate lyase from Escherichia coli 83972 (tr [KO:K01637] [EC:4.1.3.1]
KPR_0461  acs; highly similar to acetyl-coenzyme A synthetase from Salmonella typhi (sp [KO:K01895] [EC:6.2.1.1]
KPR_0376  unnamed protein product; highly similar to malate synthase from Escherichia coli O1:K1 - APEC (tr [KO:K01638] [EC:2.3.3.9]
KPR_4827  mdh; highly similar to malate dehydrogenase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00024] [EC:1.1.1.37]
KPR_3851  cisY; highly similar to citrate synthase from Salmonella typhimurium (sp [KO:K01647] [EC:2.3.3.1]
KPR_4079  unnamed protein product; similar to citrate synthase from Escherichia coli O150:H5 strain SE15 (tr [KO:K01647] [EC:2.3.3.1]
KPR_2324  acnA; highly similar to aconitate hydratase 1 from Escherichia coli strain K12 (sp [KO:K01681] [EC:4.2.1.3]
KPR_1053  acnB; highly similar to aconitate hydratase 2 from Escherichia coli B171 (tr [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KPR_1763  yqeF; highly similar to probable acetyl-CoA acetyltransferase from Escherichia coli strain K12 (sp [KO:K00626] [EC:2.3.1.9]
KPR_3090  atoB; similar to acetyl-CoA acetyltransferase from Pseudomonas aeruginosa (sp [KO:K00626] [EC:2.3.1.9]
KPR_2597  thlA; highly similar to acetyl-CoA acetyltransferase thlA from Enterobacter helveticus (tr [KO:K00626] [EC:2.3.1.9]
KPR_2285  katE; highly similar to catalase HPII from Escherichia coli strain K12 (sp [KO:K03781] [EC:1.11.1.6]
KPR_2100  ghrA; highly similar to glyoxylate/hydroxypyruvate reductase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPR_1311  unnamed protein product; weakly similar to D-isomer specific 2-hydroxyacid dehydrogenase from Acinetobacter radioresistens (tr [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KPR_5000  ghrB; highly similar to glyoxylate/hydroxypyruvate reductase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KPR_0714  gph; highly similar to phosphoglycolate phosphatase from Klebsiella aerogenes (sp [KO:K01091] [EC:3.1.3.18]
KPR_0138  glnA; highly similar to putative glutamine synthetase from Enterobacter gergoviae (tr [KO:K01915] [EC:6.3.1.2]
KPR_1397  glyA; highly similar to serine hydroxymethyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00600] [EC:2.1.2.1]
KPR_4603  gcvP; highly similar to glycine dehydrogenase [decarboxylating] from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00281] [EC:1.4.4.2]
KPR_4605  gcvT; highly similar to aminomethyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K00605] [EC:2.1.2.10]
KPR_1049  lpdA; highly similar to dihydrolipoyl dehydrogenase from Escherichia coli strain UTI89 - UPEC (tr [KO:K00382] [EC:1.8.1.4]
KPR_4604  gcvH; highly similar to glycine cleavage system H protein from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp [KO:K02437]
KPR_4743  garR; highly similar to 2-hydroxy-3-oxopropionate reductase from Escherichia coli O6:K15:H31 strain 536 - UPEC (tr [KO:K00042] [EC:1.1.1.60]
KPR_4138  unnamed protein product; highly similar to putative glycerate kinase from Enterobacter cancerogenus (tr [KO:K00865] [EC:2.7.1.165]
KPR_4742  garK; highly similar to glycerate kinase from Escherichia coli strain SMS-3-5 - SECEC (tr [KO:K00865] [EC:2.7.1.165]
KPR_2592  glxK; weakly similar to glycerate kinase from Bacillus halodurans (sp [KO:K00865] [EC:2.7.1.165]
KPR_2306  ttuD; similar to putative hydroxypyruvate reductase from Agrobacterium vitis (sp [KO:K11529] [EC:2.7.1.165]
KPR_2842  aldA; highly similar to lactaldehyde dehydrogenase from Escherichia coli strain K12 (sp [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KPR_4164  fucO; highly similar to lactaldehyde reductase from Escherichia coli strain K12 (sp [KO:K00048] [EC:1.1.1.77]
KPR_3507  ttuC; highly similar to probable tartrate dehydrogenase-decarboxylase from Escherichia coli strain K12 (sp [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPR_2305  ttuC; highly similar to probable tartrate dehydrogenase-decarboxylase TtuC from Agrobacterium vitis (sp [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KPR_3277  eda; highly similar to 2-keto-3-deoxygluconate 6-phosphate aldolase from Escherichia coli strain UTI89 - UPEC (tr [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KPR_0153  fdoG; highly similar to formate dehydrogenase-O major alpha subunit from Escherichia coli strain K12 (sp [KO:K00123] [EC:1.17.1.9]
KPR_0152  fdoH; highly similar to formate dehydrogenase-O, iron-sulfur subunit from Escherichia coli strain UTI89 - UPEC (tr [KO:K00124]
KPR_0151  fdoI; highly similar to formate dehydrogenase-O gamma subunit from Salmonella typhi (tr [KO:K00127]
KPR_3125  purU; highly similar to formyltetrahydrofolate deformylase from Shigella flexneri (sp [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
kpr00010  Glycolysis / Gluconeogenesis
kpr00020  Citrate cycle (TCA cycle)
kpr00030  Pentose phosphate pathway
kpr00053  Ascorbate and aldarate metabolism
kpr00071  Fatty acid degradation
kpr00230  Purine metabolism
kpr00250  Alanine, aspartate and glutamate metabolism
kpr00260  Glycine, serine and threonine metabolism
kpr00620  Pyruvate metabolism
kpr00710  Carbon fixation by Calvin cycle
kpr00750  Vitamin B6 metabolism
kpr00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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