KEGG   PATHWAY: lth04011
Entry
lth04011                    Pathway                                
Name
MAPK signaling pathway - yeast - Lachancea thermotolerans
Description
The S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third (Hog1) is necessary for survival under hyperosmotic conditions. A fourth (Slt2/Mpk1) is required for repair of injuries to the cell wall. As in mammalian cells, these pathways consist of a conserved module in which three kinases phosphorylate each other in sequence. The MAPK is phosphorylated by the MAPK/ERK kinase (MAPKK/MEK), which is itself phosphorylated by a MEK kinase (MAPKKK/MEKK).
Class
Environmental Information Processing; Signal transduction
Pathway map
lth04011  MAPK signaling pathway - yeast
lth04011

Other DBs
GO: 0000165
Organism
Lachancea thermotolerans [GN:lth]
Gene
KLTH0H04862g  KLTH0H04862p [KO:K11234]
KLTH0A03256g  KLTH0A03256p [KO:K11213]
KLTH0F04444g  KLTH0F04444p [KO:K04627]
KLTH0B06204g  KLTH0B06204p [KO:K02218] [EC:2.7.11.1]
KLTH0E06908g  KLTH0E06908p [KO:K10591] [EC:2.3.2.26]
KLTH0C01122g  KLTH0C01122p [KO:K19860]
KLTH0D10186g  KLTH0D10186p [KO:K04536]
KLTH0F07678g  KLTH0F07678p [KO:K07973]
KLTH0F18436g  KLTH0F18436p [KO:K19838]
KLTH0D01166g  KLTH0D01166p [KO:K11236]
KLTH0F07920g  KLTH0F07920p [KO:K04393]
KLTH0F15598g  KLTH0F15598p [KO:K19839]
KLTH0D09526g  KLTH0D09526p [KO:K19840]
KLTH0E12518g  KLTH0E12518p [KO:K11237]
KLTH0D06006g  KLTH0D06006p [KO:K04409] [EC:2.7.11.1]
KLTH0A01320g  KLTH0A01320p [KO:K19833] [EC:2.7.11.1]
KLTH0F02376g  KLTH0F02376p [KO:K11238]
KLTH0E04334g  KLTH0E04334p [KO:K11228] [EC:2.7.11.25]
KLTH0F01364g  KLTH0F01364p [KO:K19841]
KLTH0G14080g  KLTH0G14080p [KO:K11239]
KLTH0H01584g  KLTH0H01584p [KO:K11226] [EC:2.7.12.2]
KLTH0H08316g  KLTH0H08316p [KO:K04371] [EC:2.7.11.24]
KLTH0G17512g  KLTH0G17512p [KO:K04371] [EC:2.7.11.24]
KLTH0A04862g  KLTH0A04862p [KO:K19806] [EC:3.1.3.48]
KLTH0D09988g  KLTH0D09988p [KO:K19806] [EC:3.1.3.48]
KLTH0G09702g  KLTH0G09702p [KO:K11240] [EC:3.1.3.48]
KLTH0E03586g  KLTH0E03586p [KO:K11215]
KLTH0E11594g  KLTH0E11594p [KO:K11241]
KLTH0B04026g  KLTH0B04026p [KO:K12412]
KLTH0F01540g  KLTH0F01540p [KO:K11243]
KLTH0F05082g  KLTH0F05082p [KO:K06652]
KLTH0A05632g  KLTH0A05632p [KO:K06650]
KLTH0E11924g  KLTH0E11924p [KO:K04563] [EC:2.7.11.22]
KLTH0F12518g  KLTH0F12518p [KO:K11244]
KLTH0C09196g  KLTH0C09196p [KO:K11244]
KLTH0G17226g  KLTH0G17226p [KO:K11245]
KLTH0D13574g  KLTH0D13574p [KO:K19842]
KLTH0D15752g  KLTH0D15752p [KO:K19843]
KLTH0D03608g  KLTH0D03608p [KO:K00888] [EC:2.7.1.67]
KLTH0F08008g  KLTH0F08008p [KO:K00889] [EC:2.7.1.68]
KLTH0F18590g  KLTH0F18590p [KO:K04513]
KLTH0F18612g  KLTH0F18612p [KO:K04513]
KLTH0H07282g  KLTH0H07282p [KO:K19844]
KLTH0F15092g  KLTH0F15092p [KO:K19845]
KLTH0E00704g  KLTH0E00704p [KO:K17971]
KLTH0C05478g  KLTH0C05478p [KO:K02677] [EC:2.7.11.13]
KLTH0G05214g  KLTH0G05214p [KO:K06276] [EC:2.7.11.1]
KLTH0C09548g  KLTH0C09548p [KO:K06276] [EC:2.7.11.1]
KLTH0D03454g  KLTH0D03454p [KO:K11229] [EC:2.7.11.25]
KLTH0D10670g  KLTH0D10670p [KO:K08294] [EC:2.7.12.2]
KLTH0H08602g  KLTH0H08602p [KO:K19846]
KLTH0G06974g  KLTH0G06974p [KO:K04464] [EC:2.7.11.24]
KLTH0E13156g  KLTH0E13156p [KO:K09265]
KLTH0G17754g  KLTH0G17754p [KO:K00706] [EC:2.4.1.34]
KLTH0B09856g  KLTH0B09856p [KO:K00706] [EC:2.4.1.34]
KLTH0H10934g  KLTH0H10934p [KO:K15174]
KLTH0C06270g  KLTH0C06270p [KO:K06649]
KLTH0F01826g  KLTH0F01826p [KO:K06648]
KLTH0D08690g  KLTH0D08690p [KO:K02555] [EC:3.1.3.48]
KLTH0E05192g  KLTH0E05192p [KO:K23469]
KLTH0G03696g  KLTH0G03696p [KO:K19848]
KLTH0E08844g  KLTH0E08844p [KO:K19849]
KLTH0C06028g  KLTH0C06028p [KO:K11246]
KLTH0F11814g  KLTH0F11814p [KO:K19850]
KLTH0E01100g  KLTH0E01100p [KO:K11231] [EC:2.7.13.3]
KLTH0B08030g  KLTH0B08030p [KO:K11232]
KLTH0B02684g  KLTH0B02684p [KO:K11233]
KLTH0A06776g  KLTH0A06776p [KO:K11230] [EC:2.7.11.25]
KLTH0F05918g  KLTH0F05918p [KO:K11227] [EC:2.7.12.2]
KLTH0G12738g  KLTH0G12738p [KO:K04441] [EC:2.7.11.24]
KLTH0G16676g  KLTH0G16676p [KO:K19704] [EC:3.1.3.16]
KLTH0H03498g  KLTH0H03498p [KO:K19815]
KLTH0F06622g  KLTH0F06622p [KO:K00006] [EC:1.1.1.8]
KLTH0D08734g  KLTH0D08734p [KO:K09468]
KLTH0E11550g  KLTH0E11550p [KO:K03781] [EC:1.11.1.6]
KLTH0F12210g  KLTH0F12210p [KO:K03781] [EC:1.11.1.6]
KLTH0B06732g  KLTH0B06732p [KO:K09051]
KLTH0F10428g  KLTH0F10428p [KO:K06665]
KLTH0A07282g  KLTH0A07282p [KO:K06666]
KLTH0E09680g  KLTH0E09680p [KO:K17741] [EC:1.1.1.283]
KLTH0F04026g  KLTH0F04026p [KO:K17741] [EC:1.1.1.283]
KLTH0B06182g  KLTH0B06182p [KO:K17741] [EC:1.1.1.283]
KLTH0B06402g  KLTH0B06402p [KO:K17741] [EC:1.1.1.283]
KLTH0G19228g  KLTH0G19228p [KO:K03085]
KLTH0E05170g  KLTH0E05170p [KO:K06651]
KLTH0D05566g  KLTH0D05566p [KO:K02515] [EC:2.7.11.-]
KLTH0F11242g  KLTH0F11242p [KO:K02516] [EC:2.1.1.320]
KLTH0F03916g  KLTH0F03916p [KO:K03114] [EC:2.7.11.1]
KLTH0G12386g  KLTH0G12386p [KO:K06009] [EC:3.4.23.41]
KLTH0G14146g  KLTH0G14146p [KO:K06630]
KLTH0E14344g  KLTH0E14344p [KO:K09448]
Reference
PMID:15690603
  Authors
Bardwell L
  Title
A walk-through of the yeast mating pheromone response pathway.
  Journal
Peptides 26:339-50 (2005)
DOI:10.1016/j.peptides.2004.10.002
Reference
PMID:15944456
  Authors
Levin DE
  Title
Cell wall integrity signaling in Saccharomyces cerevisiae.
  Journal
Microbiol Mol Biol Rev 69:262-91 (2005)
DOI:10.1128/MMBR.69.2.262-291.2005
Reference
PMID:22174182
  Authors
Levin DE
  Title
Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.
  Journal
Genetics 189:1145-75 (2011)
DOI:10.1534/genetics.111.128264
Reference
PMID:17875410
  Authors
Hohmann S, Krantz M, Nordlander B
  Title
Yeast osmoregulation.
  Journal
Methods Enzymol 428:29-45 (2007)
DOI:10.1016/S0076-6879(07)28002-4
Reference
PMID:23028184
  Authors
Saito H, Posas F
  Title
Response to hyperosmotic stress.
  Journal
Genetics 192:289-318 (2012)
DOI:10.1534/genetics.112.140863
Reference
PMID:22219507
  Authors
Cullen PJ, Sprague GF Jr
  Title
The regulation of filamentous growth in yeast.
  Journal
Genetics 190:23-49 (2012)
DOI:10.1534/genetics.111.127456
Reference
PMID:9841672
  Authors
Gustin MC, Albertyn J, Alexander M, Davenport K
  Title
MAP kinase pathways in the yeast Saccharomyces cerevisiae.
  Journal
Microbiol Mol Biol Rev 62:1264-300 (1998)
Reference
PMID:17604854
  Authors
Chen RE, Thorner J
  Title
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1773:1311-40 (2007)
DOI:10.1016/j.bbamcr.2007.05.003
KO pathway
ko04011   
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