KEGG   PATHWAY: mab00630
Entry
mab00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacteroides abscessus ATCC 19977
Class
Metabolism; Carbohydrate metabolism
Pathway map
mab00630  Glyoxylate and dicarboxylate metabolism
mab00630

Module
mab_M00621  Glycine cleavage system [PATH:mab00630]
mab_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mab00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacteroides abscessus ATCC 19977 [GN:mab]
Gene
MAB_4095c  Isocitrate lyase (AceA) [KO:K01637] [EC:4.1.3.1]
MAB_0425c  Acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
MAB_2409c  Malate synthase G GlcB [KO:K01638] [EC:2.3.3.9]
MAB_0932c  Putative citrate synthase CitA [KO:K01647] [EC:2.3.3.1]
MAB_0944  Probable citrate synthase I (GltA) [KO:K01647] [EC:2.3.3.1]
MAB_4619  Probable citrate synthase [KO:K01647] [EC:2.3.3.1]
MAB_2730  Probable aconitate hydratase ACN [KO:K01681] [EC:4.2.1.3]
MAB_1463  Probable acetyl-CoA acetyltransferase FadA [KO:K00626] [EC:2.3.1.9]
MAB_3826c  Conserved hypothetical protein [KO:K00626] [EC:2.3.1.9]
MAB_4169  Possible lipid carrier protein or keto acyl-COA thiolase [KO:K00626] [EC:2.3.1.9]
MAB_4442c  Probable acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
MAB_0850  Probable acyl-coa thiolase FadA [KO:K00626] [EC:2.3.1.9]
MAB_0600  Probable acetyl-CoA acetyltransferase FadA [KO:K00626] [EC:2.3.1.9]
MAB_0612c  Probable acetyl-CoA acetyltransferase FadA [KO:K00626] [EC:2.3.1.9]
MAB_1192c  Probable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MAB_2042c  Conserved hypothetical protein [KO:K00626] [EC:2.3.1.9]
MAB_1462c  Conserved hypothetical protein (Glyoxalase/Bleomycin resistance protein?) [KO:K05606] [EC:5.1.99.1]
MAB_3643  Probable bifunctional protein acetyl-/propionyl-CoA carboxylase (alpha chain) AccA3 [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MAB_3631  Probable propionyl-CoA carboxylase beta chain 5 AccD5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MAB_3632  Conserved hypothetical protein [KO:K27095]
MAB_1876c  Probable propionyl-CoA carboxylase beta chain 6 [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MAB_2711c  Probable methylmalonyl-CoA mutase large subunit MutB [KO:K01847] [EC:5.4.99.2]
MAB_2712c  Probable methylmalonyl-CoA mutase small subunit MutA [KO:K01847] [EC:5.4.99.2]
MAB_1407c  Probable oxidoreductase [KO:K00104] [EC:1.1.99.14]
MAB_2530c  Catalase CatB [KO:K03781] [EC:1.11.1.6]
MAB_0351  Catalase [KO:K03781] [EC:1.11.1.6]
MAB_1842c  Probable catalase [KO:K03781] [EC:1.11.1.6]
MAB_4879c  Putative phosphatase [KO:K01091] [EC:3.1.3.18]
MAB_1901c  Conserved hypothetical protein (hydrolase?) [KO:K01091] [EC:3.1.3.18]
MAB_1920  Probable glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MAB_1933c  Probable glutamine synthetase, type I (GlnA1) [KO:K01915] [EC:6.3.1.2]
MAB_1236  Probable serine or glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MAB_2407  Glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
MAB_1949  Probable aminomethyltransferase/Glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
MAB_0894c  Putative dihydrolipoamide dehydrogenase (LpdA) [KO:K00382] [EC:1.8.1.4]
MAB_4127c  Probable dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
MAB_2402  Glycine cleavage system H protein (GcvH) [KO:K02437]
MAB_1956  Probable glycerate kinase [KO:K00865] [EC:2.7.1.165]
MAB_4419  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
MAB_1393c  Probable 2-oxoglutarate dehydrogenase SucA [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MAB_4766  Hypothetical oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
MAB_0999  Putative NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MAB_1306  Probable formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MAB_0587  Probable acetamidase/formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mab00010  Glycolysis / Gluconeogenesis
mab00020  Citrate cycle (TCA cycle)
mab00030  Pentose phosphate pathway
mab00053  Ascorbate and aldarate metabolism
mab00071  Fatty acid degradation
mab00230  Purine metabolism
mab00250  Alanine, aspartate and glutamate metabolism
mab00260  Glycine, serine and threonine metabolism
mab00620  Pyruvate metabolism
mab00710  Carbon fixation by Calvin cycle
mab00750  Vitamin B6 metabolism
mab00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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