KEGG   PATHWAY: mav00630
Entry
mav00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium avium 104
Class
Metabolism; Carbohydrate metabolism
Pathway map
mav00630  Glyoxylate and dicarboxylate metabolism
mav00630

Module
mav_M00012  Glyoxylate cycle [PATH:mav00630]
mav_M00621  Glycine cleavage system [PATH:mav00630]
mav_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mav00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium avium 104 [GN:mav]
Gene
MAV_2781  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MAV_4682  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MAV_0462  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MAV_2880  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
MAV_1380  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MAV_0344  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MAV_1016  citrate synthase [KO:K01647] [EC:2.3.3.1]
MAV_3303  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
MAV_4915  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_1544  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_5081  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_2851  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_1198  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_2702  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_1573  beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
MAV_0980  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_0604  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_0615  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_5069  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_0636  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_2584  beta-ketoadipyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
MAV_2557  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MAV_1076  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MAV_1842  lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
MAV_1817  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MAV_1596  putative thiolase [KO:K00626] [EC:2.3.1.9]
MAV_5079  thiolase [KO:K00626] [EC:2.3.1.9]
MAV_1543  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MAV_4255  acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MAV_4250  propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MAV_4251  conserved hypothetical protein [KO:K27095]
MAV_2190  propionyl-CoA carboxylase beta chain [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MAV_3277  methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
MAV_3278  mutA; methylmalonyl-CoA mutase, small subunit [KO:K01847] [EC:5.4.99.2]
MAV_0857  putative methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
MAV_0856  methylmalonyl-CoA mutase, N-terminus of large subunit [KO:K01848] [EC:5.4.99.2]
MAV_1405  oxidoreductase, FAD-binding [KO:K00104] [EC:1.1.99.14]
MAV_4069  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
MAV_4927  katA; catalase KatA [KO:K03781] [EC:1.11.1.6]
MAV_4926  katA; catalase KatA [KO:K03781] [EC:1.11.1.6]
MAV_3520  catalase [KO:K03781] [EC:1.11.1.6]
MAV_2207  conserved hypothetical protein, putative [KO:K01091] [EC:3.1.3.18]
MAV_2829  glnA; glutamine synthetase, catalytic domain [KO:K01915] [EC:6.3.1.2]
MAV_2267  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
MAV_2244  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
MAV_3718  glnA; glutamine synthetase, catalytic domain [KO:K01915] [EC:6.3.1.2]
MAV_1215  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MAV_2884  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MAV_2280  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
MAV_4687  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
MAV_2889  gcvH; glycine cleavage system H protein [KO:K02437]
MAV_2286  glycerate kinase subfamily protein [KO:K00865] [EC:2.7.1.165]
MAV_4930  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MAV_0421  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
MAV_0422  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
MAV_0423  4Fe-4S binding domain protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mav00010  Glycolysis / Gluconeogenesis
mav00020  Citrate cycle (TCA cycle)
mav00030  Pentose phosphate pathway
mav00053  Ascorbate and aldarate metabolism
mav00071  Fatty acid degradation
mav00230  Purine metabolism
mav00250  Alanine, aspartate and glutamate metabolism
mav00260  Glycine, serine and threonine metabolism
mav00620  Pyruvate metabolism
mav00710  Carbon fixation by Calvin cycle
mav00750  Vitamin B6 metabolism
mav00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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