KEGG   PATHWAY: mcb00630
Entry
mcb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium chubuense
Class
Metabolism; Carbohydrate metabolism
Pathway map
mcb00630  Glyoxylate and dicarboxylate metabolism
mcb00630

Module
mcb_M00621  Glycine cleavage system [PATH:mcb00630]
mcb_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mcb00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium chubuense [GN:mcb]
Gene
Mycch_0579  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
Mycch_2899  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
Mycch_1012  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
Mycch_4782  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Mycch_2786  malate synthase [KO:K01638] [EC:2.3.3.9]
Mycch_4398  citrate synthase I, hexameric type [KO:K01647] [EC:2.3.3.1]
Mycch_4402  citrate synthase [KO:K01647] [EC:2.3.3.1]
Mycch_2464  aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
Mycch_0230  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_2813  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4090  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_1720  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4261  hypothetical protein [KO:K00626] [EC:2.3.1.9]
Mycch_5919  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4324  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_5171  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_3585  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4433  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4652  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_0288  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4583  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_3750  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_4639  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Mycch_3751  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Mycch_1265  acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Mycch_1289  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Mycch_1288  hypothetical protein [KO:K27095]
Mycch_3280  acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Mycch_2479  methylmalonyl-CoA mutase, heterodimeric type, beta chain [KO:K01847] [EC:5.4.99.2]
Mycch_2480  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Mycch_3704  methylmalonyl-CoA mutase family protein [KO:K01849] [EC:5.4.99.2]
Mycch_3705  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Mycch_3859  FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
Mycch_4834  catalase [KO:K03781] [EC:1.11.1.6]
Mycch_0031  catalase [KO:K03781] [EC:1.11.1.6]
Mycch_0048  phosphonatase-like hydrolase [KO:K01091] [EC:3.1.3.18]
Mycch_3254  putative phosphatase [KO:K01091] [EC:3.1.3.18]
Mycch_3226  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Mycch_3234  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Mycch_0036  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mycch_2843  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mycch_2019  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Mycch_4844  gamma-glutamylmethylamide synthetase [KO:K01915] [EC:6.3.1.2]
Mycch_4068  glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mycch_2757  glycine dehydrogenase, decarboxylating [KO:K00281] [EC:1.4.4.2]
Mycch_3214  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Mycch_0573  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Mycch_2752  glycine cleavage system H protein [KO:K02437]
Mycch_3463  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Mycch_3208  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Mycch_4284  2-keto-3-deoxy-6-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Mycch_3880  2-oxoglutarate dehydrogenase E1 component [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Mycch_3840  anaerobic dehydrogenase, typically selenocysteine-containing [KO:K00122] [EC:1.17.1.9]
Mycch_0823  anaerobic dehydrogenase, typically selenocysteine-containing [KO:K00123] [EC:1.17.1.9]
Mycch_0824  Fe-S-cluster-containing hydrogenase subunit [KO:K00124]
Mycch_0907  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Mycch_2299  putative acetamidase/formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mcb00010  Glycolysis / Gluconeogenesis
mcb00020  Citrate cycle (TCA cycle)
mcb00030  Pentose phosphate pathway
mcb00053  Ascorbate and aldarate metabolism
mcb00071  Fatty acid degradation
mcb00230  Purine metabolism
mcb00250  Alanine, aspartate and glutamate metabolism
mcb00260  Glycine, serine and threonine metabolism
mcb00620  Pyruvate metabolism
mcb00710  Carbon fixation by Calvin cycle
mcb00750  Vitamin B6 metabolism
mcb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system