KEGG   PATHWAY: mchl00630
Entry
mchl00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Micromonospora chalcea
Class
Metabolism; Carbohydrate metabolism
Pathway map
mchl00630  Glyoxylate and dicarboxylate metabolism
mchl00630

Module
mchl_M00621  Glycine cleavage system [PATH:mchl00630]
Other DBs
GO: 0046487 0043648
Organism
Micromonospora chalcea [GN:mchl]
Gene
PVK74_23205  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
PVK74_17090  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
PVK74_04485  citrate synthase [KO:K01647] [EC:2.3.3.1]
PVK74_23660  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
PVK74_11440  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
PVK74_03195  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
PVK74_03205  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
PVK74_15765  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
PVK74_22050  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
PVK74_25835  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
PVK74_09670  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
PVK74_15770  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
PVK74_15850  protein meaA [KO:K14447] [EC:5.4.99.63]
PVK74_25410  biotin carboxylase N-terminal domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
PVK74_25505  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
PVK74_25305  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
PVK74_18860  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
PVK74_22700  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
PVK74_01105  catalase [KO:K03781] [EC:1.11.1.6]
PVK74_23575  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
PVK74_03705  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
PVK74_13235  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
PVK74_13300  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
PVK74_28465  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
PVK74_07570  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PVK74_15975  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PVK74_30730  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
PVK74_06320  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
PVK74_13115  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
PVK74_30720  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
PVK74_13130  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
PVK74_06370  gcvH; glycine cleavage system protein GcvH [KO:K02437]
PVK74_30725  gcvH; glycine cleavage system protein GcvH [KO:K02437]
PVK74_22210  NAD(P)-binding domain-containing protein [KO:K00042] [EC:1.1.1.60]
PVK74_13025  glycerate kinase [KO:K00865] [EC:2.7.1.165]
PVK74_07910  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PVK74_16340  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
PVK74_06470  fdh; formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
PVK74_06465  4Fe-4S dicluster domain-containing protein [KO:K00124]
PVK74_00200  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mchl00010  Glycolysis / Gluconeogenesis
mchl00020  Citrate cycle (TCA cycle)
mchl00030  Pentose phosphate pathway
mchl00053  Ascorbate and aldarate metabolism
mchl00071  Fatty acid degradation
mchl00230  Purine metabolism
mchl00250  Alanine, aspartate and glutamate metabolism
mchl00260  Glycine, serine and threonine metabolism
mchl00620  Pyruvate metabolism
mchl00710  Carbon fixation by Calvin cycle
mchl00750  Vitamin B6 metabolism
mchl00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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