KEGG   PATHWAY: mesc00630
Entry
mesc00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Manihot esculenta (cassava)
Class
Metabolism; Carbohydrate metabolism
Pathway map
mesc00630  Glyoxylate and dicarboxylate metabolism
mesc00630

Module
mesc_M00012  Glyoxylate cycle [PATH:mesc00630]
mesc_M00532  Photorespiration [PATH:mesc00630]
mesc_M00621  Glycine cleavage system [PATH:mesc00630]
Other DBs
GO: 0046487 0043648
Organism
Manihot esculenta (cassava) [GN:mesc]
Gene
110629767  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
110628026  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
110613842  acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal isoform X1 [KO:K01895] [EC:6.2.1.1]
110625772  acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal isoform X1 [KO:K01895] [EC:6.2.1.1]
122721204  acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal-like isoform X1 [KO:K01895] [EC:6.2.1.1]
110602102  acetate--CoA ligase CCL3 [KO:K01913] [EC:6.2.1.1 6.2.1.2]
110600764  acetate--CoA ligase CCL3 isoform X1 [KO:K01913] [EC:6.2.1.1 6.2.1.2]
110599828  malate synthase, glyoxysomal [KO:K01638] [EC:2.3.3.9]
110601852  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
110616095  malate dehydrogenase isoform X1 [KO:K00025] [EC:1.1.1.37]
110616328  malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
110629152  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
110612281  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
110618260  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
110599910  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
110611797  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
110601163  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
110630047  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
110618870  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
110619403  citrate synthase, mitochondrial isoform X1 [KO:K01647] [EC:2.3.3.1]
110609079  citrate synthase, glyoxysomal [KO:K01647] [EC:2.3.3.1]
110600607  citrate synthase, glyoxysomal [KO:K01647] [EC:2.3.3.1]
110625172  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
110609582  aconitate hydratase 1 isoform X1 [KO:K01681] [EC:4.2.1.3]
110629776  aconitate hydratase, cytoplasmic [KO:K01681] [EC:4.2.1.3]
110627474  aconitate hydratase, cytoplasmic [KO:K01681] [EC:4.2.1.3]
110611409  aconitate hydratase, cytoplasmic isoform X1 [KO:K01681] [EC:4.2.1.3]
110630588  acetyl-CoA acetyltransferase, cytosolic 1 [KO:K00626] [EC:2.3.1.9]
110620415  acetyl-CoA acetyltransferase, cytosolic 1 isoform X1 [KO:K00626] [EC:2.3.1.9]
110627475  acetyl-CoA acetyltransferase, cytosolic 1 [KO:K00626] [EC:2.3.1.9]
110600955  peroxisomal (S)-2-hydroxy-acid oxidase isoform X1 [KO:K11517] [EC:1.1.3.15]
110604412  (S)-2-hydroxy-acid oxidase GLO1 isoform X1 [KO:K11517] [EC:1.1.3.15]
110625860  peroxisomal (S)-2-hydroxy-acid oxidase GLO4 isoform X1 [KO:K11517] [EC:1.1.3.15]
110627015  peroxisomal (S)-2-hydroxy-acid oxidase GLO4 [KO:K11517] [EC:1.1.3.15]
110607542  catalase isozyme 1 [KO:K03781] [EC:1.11.1.6]
110606601  catalase isozyme 2 [KO:K03781] [EC:1.11.1.6]
110606602  catalase isozyme 1 isoform X2 [KO:K03781] [EC:1.11.1.6]
110621051  LOW QUALITY PROTEIN: catalase-2-like [KO:K03781] [EC:1.11.1.6]
110615231  catalase isozyme 1 [KO:K03781] [EC:1.11.1.6]
110615233  catalase isozyme 2 [KO:K03781] [EC:1.11.1.6]
110628293  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
110614536  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
110614547  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
110614991  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
110626175  glyoxylate/succinic semialdehyde reductase 2, chloroplastic [KO:K18121] [EC:1.1.1.79 1.1.1.-]
110629014  glyoxylate/succinic semialdehyde reductase 1 [KO:K18121] [EC:1.1.1.79 1.1.1.-]
110614212  glycerate dehydrogenase [KO:K15893] [EC:1.1.1.29]
110620203  phosphoglycolate phosphatase 2 [KO:K19269] [EC:3.1.3.18 3.1.3.48]
110630102  phosphoglycolate phosphatase 1A, chloroplastic [KO:K19269] [EC:3.1.3.18 3.1.3.48]
5999955  rbcL; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit [KO:K01601] [EC:4.1.1.39]
110616119  ribulose bisphosphate carboxylase small subunit, chloroplastic [KO:K01602] [EC:4.1.1.39]
110627565  ribulose bisphosphate carboxylase small subunit, chloroplastic-like [KO:K01602] [EC:4.1.1.39]
110616814  ribulose bisphosphate carboxylase small subunit, chloroplastic 3 [KO:K01602] [EC:4.1.1.39]
110609356  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
110600432  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
110627295  glutamate--glyoxylate aminotransferase 2 [KO:K14272] [EC:2.6.1.4 2.6.1.2 2.6.1.44]
110629550  glutamate--glyoxylate aminotransferase 2 isoform X1 [KO:K14272] [EC:2.6.1.4 2.6.1.2 2.6.1.44]
110622961  ferredoxin-dependent glutamate synthase, chloroplastic [KO:K00284] [EC:1.4.7.1]
110611845  glutamine synthetase leaf isozyme, chloroplastic [KO:K01915] [EC:6.3.1.2]
110614029  glutamine synthetase nodule isozyme [KO:K01915] [EC:6.3.1.2]
110602694  glutamine synthetase cytosolic isozyme [KO:K01915] [EC:6.3.1.2]
110599891  glutamine synthetase nodule isozyme [KO:K01915] [EC:6.3.1.2]
110601861  serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
110604068  serine hydroxymethyltransferase 3, chloroplastic [KO:K00600] [EC:2.1.2.1]
110606415  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
110628494  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
110610302  serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
110619493  serine hydroxymethyltransferase 7 [KO:K00600] [EC:2.1.2.1]
110630137  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
110602559  serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
110607048  serine hydroxymethyltransferase 7 isoform X1 [KO:K00600] [EC:2.1.2.1]
110604177  glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
110605214  aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
110611729  dihydrolipoyl dehydrogenase 2, chloroplastic isoform X1 [KO:K00382] [EC:1.8.1.4]
110602122  dihydrolipoyl dehydrogenase 2, chloroplastic isoform X1 [KO:K00382] [EC:1.8.1.4]
110612238  dihydrolipoyl dehydrogenase 1, mitochondrial [KO:K00382] [EC:1.8.1.4]
110601243  glycine cleavage system H protein, mitochondrial [KO:K02437]
110618689  glycine cleavage system H protein 2, mitochondrial [KO:K02437]
110612515  D-glycerate 3-kinase, chloroplastic isoform X1 [KO:K15918] [EC:2.7.1.31]
110600871  formate dehydrogenase, mitochondrial [KO:K00122] [EC:1.17.1.9]
110605475  formate dehydrogenase, mitochondrial [KO:K00122] [EC:1.17.1.9]
110619099  formyltetrahydrofolate deformylase 1, mitochondrial [KO:K01433] [EC:3.5.1.10]
110628275  formamidase isoform X2 [KO:K01455] [EC:3.5.1.49]
110627757  probable CoA ligase CCL9 [KO:K22133] [EC:6.2.1.8]
110630700  probable CoA ligase CCL9 [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mesc00010  Glycolysis / Gluconeogenesis
mesc00020  Citrate cycle (TCA cycle)
mesc00030  Pentose phosphate pathway
mesc00053  Ascorbate and aldarate metabolism
mesc00071  Fatty acid degradation
mesc00230  Purine metabolism
mesc00250  Alanine, aspartate and glutamate metabolism
mesc00260  Glycine, serine and threonine metabolism
mesc00620  Pyruvate metabolism
mesc00710  Carbon fixation by Calvin cycle
mesc00750  Vitamin B6 metabolism
mesc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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