KEGG   PATHWAY: mko00630
Entry
mko00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylomonas koyamae
Class
Metabolism; Carbohydrate metabolism
Pathway map
mko00630  Glyoxylate and dicarboxylate metabolism
mko00630

Module
mko_M00621  Glycine cleavage system [PATH:mko00630]
Other DBs
GO: 0046487 0043648
Organism
Methylomonas koyamae [GN:mko]
Gene
MKLM6_2189  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
MKLM6_1851  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MKLM6_3854  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
MKLM6_1981  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
MKLM6_2354  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
MKLM6_1754  succinate--CoA ligase subunit alpha [KO:K08692] [EC:6.2.1.9]
MKLM6_1753  succinate--CoA ligase subunit beta [KO:K14067] [EC:6.2.1.9]
MKLM6_1752  Citryl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
MKLM6_2787  Glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
MKLM6_2788  Glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
MKLM6_0985  hypothetical protein [KO:K11473] [EC:1.1.99.14]
MKLM6_2789  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
MKLM6_3842  hydrolase [KO:K01091] [EC:3.1.3.18]
MKLM6_1746  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
MKLM6_2955  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MKLM6_1848  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MKLM6_1053  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MKLM6_1054  glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
MKLM6_0165  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
MKLM6_3805  glycine cleavage system protein H [KO:K02437]
MKLM6_2972  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
MKLM6_1849  glycerate kinase [KO:K11529] [EC:2.7.1.165]
MKLM6_2898  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
MKLM6_1648  formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
MKLM6_3482  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
MKLM6_3307  NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
MKLM6_3480  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MKLM6_3306  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
MKLM6_3479  formate dehydrogenase [KO:K00124]
MKLM6_3478  formate dehydrogenase subunit gamma [KO:K00127]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mko00010  Glycolysis / Gluconeogenesis
mko00020  Citrate cycle (TCA cycle)
mko00030  Pentose phosphate pathway
mko00053  Ascorbate and aldarate metabolism
mko00071  Fatty acid degradation
mko00230  Purine metabolism
mko00250  Alanine, aspartate and glutamate metabolism
mko00260  Glycine, serine and threonine metabolism
mko00620  Pyruvate metabolism
mko00710  Carbon fixation by Calvin cycle
mko00750  Vitamin B6 metabolism
mko00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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