KEGG   PATHWAY: mmon00630
Entry
mmon00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium monacense
Class
Metabolism; Carbohydrate metabolism
Pathway map
mmon00630  Glyoxylate and dicarboxylate metabolism
mmon00630

Module
mmon_M00621  Glycine cleavage system [PATH:mmon00630]
mmon_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mmon00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium monacense [GN:mmon]
Gene
EWR22_01030  isocitrate lyase family protein [KO:K01637] [EC:4.1.3.1]
EWR22_03355  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EWR22_24050  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
EWR22_25990  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EWR22_14940  malate synthase G [KO:K01638] [EC:2.3.3.9]
EWR22_24140  citrate synthase [KO:K01647] [EC:2.3.3.1]
EWR22_24155  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
EWR22_12445  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
EWR22_14815  hypothetical protein [KO:K00626] [EC:2.3.1.9]
EWR22_16370  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EWR22_19780  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_21100  thiolase family protein [KO:K00626] [EC:2.3.1.9]
EWR22_21305  thiolase family protein [KO:K00626] [EC:2.3.1.9]
EWR22_22470  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_23370  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_24335  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_25070  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EWR22_25310  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EWR22_25375  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_01305  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_07720  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_08930  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
EWR22_08985  thiolase family protein [KO:K00626] [EC:2.3.1.9]
EWR22_09035  thiolase family protein [KO:K00626] [EC:2.3.1.9]
EWR22_19785  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
EWR22_06865  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
EWR22_06890  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
EWR22_06885  acyl-CoA carboxylase subunit epsilon [KO:K27095]
EWR22_17430  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
EWR22_16485  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
EWR22_16490  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
EWR22_19575  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
EWR22_19580  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
EWR22_20425  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
EWR22_27290  catalase [KO:K03781] [EC:1.11.1.6]
EWR22_17315  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EWR22_14625  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EWR22_17175  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EWR22_17220  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EWR22_26425  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EWR22_28730  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EWR22_10445  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EWR22_02720  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EWR22_04600  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EWR22_22365  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EWR22_15055  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
EWR22_17120  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
EWR22_03330  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EWR22_15080  gcvH; glycine cleavage system protein GcvH [KO:K02437]
EWR22_28745  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EWR22_10165  glycerate kinase [KO:K00865] [EC:2.7.1.165]
EWR22_13065  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EWR22_20490  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
EWR22_28110  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
EWR22_28115  4Fe-4S dicluster domain-containing protein [KO:K00124]
EWR22_11530  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mmon00010  Glycolysis / Gluconeogenesis
mmon00020  Citrate cycle (TCA cycle)
mmon00030  Pentose phosphate pathway
mmon00053  Ascorbate and aldarate metabolism
mmon00071  Fatty acid degradation
mmon00230  Purine metabolism
mmon00250  Alanine, aspartate and glutamate metabolism
mmon00260  Glycine, serine and threonine metabolism
mmon00620  Pyruvate metabolism
mmon00710  Carbon fixation by Calvin cycle
mmon00750  Vitamin B6 metabolism
mmon00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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