KEGG   PATHWAY: mprn00630
Entry
mprn00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Micromonospora profundi
Class
Metabolism; Carbohydrate metabolism
Pathway map
mprn00630  Glyoxylate and dicarboxylate metabolism
mprn00630

Module
mprn_M00621  Glycine cleavage system [PATH:mprn00630]
Other DBs
GO: 0046487 0043648
Organism
Micromonospora profundi [GN:mprn]
Gene
Q3V37_05065  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Q3V37_11055  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Q3V37_20540  citrate synthase [KO:K01647] [EC:2.3.3.1]
Q3V37_04610  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
Q3V37_16840  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Q3V37_12425  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Q3V37_18240  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Q3V37_19095  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Q3V37_19205  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Q3V37_28855  thiolase family protein [KO:K00626] [EC:2.3.1.9]
Q3V37_02460  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Q3V37_04275  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Q3V37_12420  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Q3V37_12330  protein meaA [KO:K14447] [EC:5.4.99.63]
Q3V37_02860  biotin carboxylase N-terminal domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Q3V37_02780  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Q3V37_25245  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Q3V37_25250  methylmalonyl-CoA mutase family protein [KO:K01847] [EC:5.4.99.2]
Q3V37_02945  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
Q3V37_09255  FAD-linked oxidase C-terminal domain-containing protein [KO:K00104] [EC:1.1.99.14]
Q3V37_05550  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
Q3V37_24085  catalase [KO:K03781] [EC:1.11.1.6]
Q3V37_04680  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
Q3V37_14845  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Q3V37_14985  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Q3V37_30925  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
Q3V37_12240  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Q3V37_22730  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Q3V37_22150  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Q3V37_15375  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
Q3V37_15360  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Q3V37_22200  gcvH; glycine cleavage system protein GcvH [KO:K02437]
Q3V37_15450  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Q3V37_23460  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Q3V37_04180  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Q3V37_11820  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Q3V37_22315  fdh; formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
Q3V37_24200  fdh; formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
Q3V37_22310  4Fe-4S dicluster domain-containing protein [KO:K00124]
Q3V37_24195  4Fe-4S dicluster domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mprn00010  Glycolysis / Gluconeogenesis
mprn00020  Citrate cycle (TCA cycle)
mprn00030  Pentose phosphate pathway
mprn00053  Ascorbate and aldarate metabolism
mprn00071  Fatty acid degradation
mprn00230  Purine metabolism
mprn00250  Alanine, aspartate and glutamate metabolism
mprn00260  Glycine, serine and threonine metabolism
mprn00620  Pyruvate metabolism
mprn00710  Carbon fixation by Calvin cycle
mprn00750  Vitamin B6 metabolism
mprn00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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