KEGG   PATHWAY: mpru00630
Entry
mpru00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Metallosphaera prunae
Class
Metabolism; Carbohydrate metabolism
Pathway map
mpru00630  Glyoxylate and dicarboxylate metabolism
mpru00630

Module
mpru_M00621  Glycine cleavage system [PATH:mpru00630]
mpru_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mpru00630]
Other DBs
GO: 0046487 0043648
Organism
Metallosphaera prunae [GN:mpru]
Gene
DFR88_11870  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DFR88_11560  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DFR88_05280  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DFR88_01310  malate synthase [KO:K01638] [EC:2.3.3.9]
DFR88_04310  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DFR88_10690  citrate synthase [KO:K01647] [EC:2.3.3.1]
DFR88_05210  citrate synthase [KO:K01647] [EC:2.3.3.1]
DFR88_10975  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
DFR88_03300  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
DFR88_04605  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR88_05260  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR88_05265  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR88_04675  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DFR88_10035  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DFR88_11880  thiolase family protein [KO:K00626] [EC:2.3.1.9]
DFR88_03385  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DFR88_00425  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
DFR88_05905  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01964] [EC:6.4.1.2 6.4.1.3]
DFR88_11445  acyl-CoA carboxylase subunit beta [KO:K15036] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
DFR88_05900  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit [KO:K15037]
DFR88_07885  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
DFR88_03390  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DFR88_03825  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DFR88_00935  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
DFR88_04405  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DFR88_03830  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
DFR88_03820  (Fe-S)-binding protein [KO:K11473] [EC:1.1.99.14]
DFR88_05335  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
DFR88_07500  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
DFR88_02920  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
DFR88_03580  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DFR88_10215  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DFR88_10020  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DFR88_09930  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
DFR88_09925  glycine dehydrogenase (aminomethyl-transferring) [KO:K00283] [EC:1.4.4.2]
DFR88_09935  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DFR88_10545  NAD(P)/FAD-dependent oxidoreductase [KO:K00382] [EC:1.8.1.4]
DFR88_08125  NAD(P)/FAD-dependent oxidoreductase [KO:K00382] [EC:1.8.1.4]
DFR88_01065  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DFR88_08320  NAD(P)/FAD-dependent oxidoreductase [KO:K00382] [EC:1.8.1.4]
DFR88_10905  glycine cleavage system protein H [KO:K02437]
DFR88_09940  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DFR88_10450  glycine cleavage system protein H [KO:K02437]
DFR88_08105  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
DFR88_11730  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DFR88_11025  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
DFR88_11770  cyclase family protein [KO:K07130] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mpru00010  Glycolysis / Gluconeogenesis
mpru00020  Citrate cycle (TCA cycle)
mpru00030  Pentose phosphate pathway
mpru00071  Fatty acid degradation
mpru00230  Purine metabolism
mpru00250  Alanine, aspartate and glutamate metabolism
mpru00260  Glycine, serine and threonine metabolism
mpru00620  Pyruvate metabolism
mpru00710  Carbon fixation by Calvin cycle
mpru00750  Vitamin B6 metabolism
mpru00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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