KEGG   PATHWAY: mtg00630
Entry
mtg00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium tuberculosis RGTB327
Class
Metabolism; Carbohydrate metabolism
Pathway map
mtg00630  Glyoxylate and dicarboxylate metabolism
mtg00630

Module
mtg_M00621  Glycine cleavage system [PATH:mtg00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium tuberculosis RGTB327 [GN:mtg]
Gene
MRGA327_11800  isocitrate lyase aceAa [KO:K01637] [EC:4.1.3.1]
MRGA327_11805  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MRGA327_02950  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MRGA327_22575  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
MRGA327_11360  malate synthase G [KO:K01638] [EC:2.3.3.9]
MRGA327_07780  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
MRGA327_07075  citrate synthase [KO:K01647] [EC:2.3.3.1]
MRGA327_05625  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
MRGA327_06710  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_01560  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_05390  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_21905  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_21960  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_08285  putative acyltransferase [KO:K00626] [EC:2.3.1.9]
MRGA327_08280  hypothetical protein [KO:K05606] [EC:5.1.99.1]
MRGA327_20215  propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MRGA327_20190  propionyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MRGA327_20195  hypothetical protein [KO:K27095]
MRGA327_13875  acetyl/propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MRGA327_07885  putative oxidoreductase [KO:K00104] [EC:1.1.99.14]
MRGA327_11600  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MRGA327_17535  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MRGA327_13720  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
MRGA327_00455  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MRGA327_06845  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MRGA327_11330  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MRGA327_13635  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
MRGA327_02925  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
MRGA327_11305  glycine cleavage system protein H [KO:K02437]
MRGA327_13605  hypothetical protein [KO:K00865] [EC:2.7.1.165]
MRGA327_18220  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
MRGA327_00780  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mtg00010  Glycolysis / Gluconeogenesis
mtg00020  Citrate cycle (TCA cycle)
mtg00030  Pentose phosphate pathway
mtg00053  Ascorbate and aldarate metabolism
mtg00071  Fatty acid degradation
mtg00230  Purine metabolism
mtg00250  Alanine, aspartate and glutamate metabolism
mtg00260  Glycine, serine and threonine metabolism
mtg00620  Pyruvate metabolism
mtg00710  Carbon fixation by Calvin cycle
mtg00750  Vitamin B6 metabolism
mtg00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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