KEGG   PATHWAY: mtk00310
Entry
mtk00310                    Pathway                                
Name
Lysine degradation - Mycobacterium tuberculosis KZN 4207
Class
Metabolism; Amino acid metabolism
Pathway map
mtk00310  Lysine degradation
mtk00310

Other DBs
GO: 0006554
Organism
Mycobacterium tuberculosis KZN 4207 [GN:mtk]
Gene
TBSG_03364  piperideine-6-carboxylic acid dehydrogenase pcd [KO:K26061]
TBSG_00469  dihydrolipoamide dehydrogenase lpd [KO:K00382] [EC:1.8.1.4]
TBSG_00404  acyl-CoA dehydrogenase fadE7 [KO:K00252] [EC:1.3.8.6]
TBSG_02934  enoyl-CoA hydratase echA8 [KO:K01692] [EC:4.2.1.17]
TBSG_01498  enoyl-CoA hydratase echA14 [KO:K01692] [EC:4.2.1.17]
TBSG_02521  enoyl-CoA hydratase echA12 [KO:K01692] [EC:4.2.1.17]
TBSG_00935  enoyl-CoA hydratase echA17 [KO:K01692] [EC:4.2.1.17]
TBSG_03150  fatty-acid oxidation protein fadB [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
TBSG_00248  acetyl-CoA acyltransferase fadA2 [KO:K00626] [EC:2.3.1.9]
TBSG_02138  conserved hypothetical protein [KO:K00626] [EC:2.3.1.9]
TBSG_02669  acetyl-CoA acetyltransferase fadA4 [KO:K00626] [EC:2.3.1.9]
TBSG_02929  beta-ketoacyl CoA thiolase fadA3 [KO:K00626] [EC:2.3.1.9]
TBSG_03589  lipid carrier protein or keto acyl-CoA thiolase ltp3 [KO:K00626] [EC:2.3.1.9]
TBSG_03612  acetyl-CoA acetyltransferase fadA5 [KO:K00626] [EC:2.3.1.9]
TBSG_03622  acetyl-CoA acetyltransferase fadA6 [KO:K00626] [EC:2.3.1.9]
TBSG_03151  acyl-CoA thiolase fadA [KO:K00626] [EC:2.3.1.9]
TBSG_03095  lipid carrier protein or keto acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
TBSG_01393  4-aminobutyrate aminotransferase gabT [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
TBSG_00238  succinate-semialdehyde dehydrogenase [NADP+] dependent gabD1 [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
TBSG_02277  succinate-semialdehyde dehydrogenase [NADP+]-dependent gabD2 [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
TBSG_02289  conserved hypothetical protein [KO:K18013] [EC:2.3.1.247]
TBSG_00150  aldehyde dehydrogenase NAD-dependent [KO:K00128] [EC:1.2.1.3]
TBSG_00226  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
TBSG_00788  aldehyde dehydrogenase NAD-dependent aldA [KO:K00128] [EC:1.2.1.3]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
mtk00020  Citrate cycle (TCA cycle)
mtk00300  Lysine biosynthesis
mtk00311  Penicillin and cephalosporin biosynthesis
mtk00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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