KEGG   PATHWAY: mtr00630
Entry
mtr00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Medicago truncatula (barrel medic)
Class
Metabolism; Carbohydrate metabolism
Pathway map
mtr00630  Glyoxylate and dicarboxylate metabolism
mtr00630

Module
mtr_M00012  Glyoxylate cycle [PATH:mtr00630]
mtr_M00532  Photorespiration [PATH:mtr00630]
mtr_M00621  Glycine cleavage system [PATH:mtr00630]
Other DBs
GO: 0046487 0043648
Organism
Medicago truncatula (barrel medic) [GN:mtr]
Gene
25492112  isocitrate lyase 2 [KO:K01637] [EC:4.1.3.1 4.1.3.30]
11437257  acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal [KO:K01895] [EC:6.2.1.1]
11422889  acetate/butyrate--CoA ligase AAE7, peroxisomal [KO:K01913] [EC:6.2.1.1 6.2.1.2]
25486581  acetate/butyrate--CoA ligase AAE7, peroxisomal [KO:K01913] [EC:6.2.1.1 6.2.1.2]
25500778  malate synthase, glyoxysomal [KO:K01638] [EC:2.3.3.9]
11436578  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
11430390  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
25484448  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
25502524  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
11405683  malate dehydrogenase 2, peroxisomal [KO:K00026] [EC:1.1.1.37]
11420535  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
120580136  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
11445289  citrate synthase, glyoxysomal isoform X1 [KO:K01647] [EC:2.3.3.1]
11437065  citrate synthase, glyoxysomal [KO:K01647] [EC:2.3.3.1]
25486862  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
11416041  aconitate hydratase, cytoplasmic [KO:K01681] [EC:4.2.1.3]
11440920  aconitate hydratase, cytoplasmic [KO:K01681] [EC:4.2.1.3]
11421844  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
25481093  acetyl-CoA acetyltransferase, cytosolic 1 [KO:K00626] [EC:2.3.1.9]
25494326  LOW QUALITY PROTEIN: acetyl-CoA acetyltransferase, cytosolic 1 [KO:K00626] [EC:2.3.1.9]
11424070  acetyl-CoA acetyltransferase, cytosolic 1 [KO:K00626] [EC:2.3.1.9]
25487060  peroxisomal (S)-2-hydroxy-acid oxidase isoform X1 [KO:K11517] [EC:1.1.3.15]
120577450  (S)-2-hydroxy-acid oxidase GLO1-like [KO:K11517] [EC:1.1.3.15]
120577451  (S)-2-hydroxy-acid oxidase GLO1-like [KO:K11517] [EC:1.1.3.15]
120577452  (S)-2-hydroxy-acid oxidase GLO1-like [KO:K11517] [EC:1.1.3.15]
120577602  (S)-2-hydroxy-acid oxidase GLO1-like isoform X1 [KO:K11517] [EC:1.1.3.15]
120577617  (S)-2-hydroxy-acid oxidase GLO1-like isoform X1 [KO:K11517] [EC:1.1.3.15]
25490307  catalase-4 [KO:K03781] [EC:1.11.1.6]
25500999  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
25501000  glyoxylate/hydroxypyruvate reductase HPR3 [KO:K15919] [EC:1.1.1.79 1.1.1.81]
25500766  glyoxylate/succinic semialdehyde reductase 1 [KO:K18121] [EC:1.1.1.79 1.1.1.-]
11432939  glyoxylate/succinic semialdehyde reductase 2, chloroplastic [KO:K18121] [EC:1.1.1.79 1.1.1.-]
25485608  glycerate dehydrogenase [KO:K15893] [EC:1.1.1.29]
11410757  phosphoglycolate phosphatase 2 [KO:K19269] [EC:3.1.3.18 3.1.3.48]
11436721  phosphoglycolate phosphatase 1A, chloroplastic [KO:K19269] [EC:3.1.3.18 3.1.3.48]
120576791  ribulose bisphosphate carboxylase large chain-like [KO:K01601] [EC:4.1.1.39]
120579494  ribulose bisphosphate carboxylase large chain-like [KO:K01601] [EC:4.1.1.39]
120580073  ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
120580927  ribulose bisphosphate carboxylase large chain-like [KO:K01601] [EC:4.1.1.39]
5333101  rbcL; ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit [KO:K01601] [EC:4.1.1.39]
25497418  ribulose bisphosphate carboxylase small chain 3A, chloroplastic [KO:K01602] [EC:4.1.1.39]
112416064  ribulose bisphosphate carboxylase small chain 3A, chloroplastic [KO:K01602] [EC:4.1.1.39]
25497422  ribulose bisphosphate carboxylase small chain 3A, chloroplastic [KO:K01602] [EC:4.1.1.39]
25497424  ribulose bisphosphate carboxylase small chain 3A, chloroplastic [KO:K01602] [EC:4.1.1.39]
25497425  ribulose bisphosphate carboxylase small chain 3A, chloroplastic [KO:K01602] [EC:4.1.1.39]
11446762  ribulose bisphosphate carboxylase small chain clone 512 [KO:K01602] [EC:4.1.1.39]
11420076  ribulose bisphosphate carboxylase small chain, chloroplastic isoform X3 [KO:K01602] [EC:4.1.1.39]
11440516  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
11423326  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
11409437  glutamate--glyoxylate aminotransferase 2 isoform X1 [KO:K14272] [EC:2.6.1.4 2.6.1.2 2.6.1.44]
11415038  ferredoxin-dependent glutamate synthase, chloroplastic [KO:K00284] [EC:1.4.7.1]
11406645  glutamine synthetase cytosolic isozyme [KO:K01915] [EC:6.3.1.2]
11431638  glutamine synthetase nodule isozyme [KO:K01915] [EC:6.3.1.2]
120575736  glutamine synthetase leaf isozyme, chloroplastic-like [KO:K01915] [EC:6.3.1.2]
25486062  glutamine synthetase leaf isozyme, chloroplastic [KO:K01915] [EC:6.3.1.2]
11427840  glutamine synthetase nodule isozyme [KO:K01915] [EC:6.3.1.2]
11445860  serine hydroxymethyltransferase 3, chloroplastic [KO:K00600] [EC:2.1.2.1]
11415840  serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
11424199  serine hydroxymethyltransferase 6 [KO:K00600] [EC:2.1.2.1]
11420162  serine hydroxymethyltransferase 7 [KO:K00600] [EC:2.1.2.1]
11442479  serine hydroxymethyltransferase 4 [KO:K00600] [EC:2.1.2.1]
11405458  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
11429401  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
11415278  glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
11437303  aminomethyltransferase, mitochondrial isoform X1 [KO:K00605] [EC:2.1.2.10]
11408806  dihydrolipoyl dehydrogenase 2, chloroplastic isoform X1 [KO:K00382] [EC:1.8.1.4]
11422305  dihydrolipoyl dehydrogenase 1, chloroplastic [KO:K00382] [EC:1.8.1.4]
25494137  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
11443425  glycine cleavage system H protein 2, mitochondrial [KO:K02437]
11433975  glycine cleavage system H protein, mitochondrial [KO:K02437]
11436362  D-glycerate 3-kinase, chloroplastic [KO:K15918] [EC:2.7.1.31]
25495172  formate dehydrogenase 1, mitochondrial [KO:K00122] [EC:1.17.1.9]
11426938  formyltetrahydrofolate deformylase 1, mitochondrial [KO:K01433] [EC:3.5.1.10]
11428500  formyltetrahydrofolate deformylase 1, mitochondrial [KO:K01433] [EC:3.5.1.10]
25493523  formamidase isoform X2 [KO:K01455] [EC:3.5.1.49]
11407788  oxalate--CoA ligase [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mtr00010  Glycolysis / Gluconeogenesis
mtr00020  Citrate cycle (TCA cycle)
mtr00030  Pentose phosphate pathway
mtr00053  Ascorbate and aldarate metabolism
mtr00071  Fatty acid degradation
mtr00230  Purine metabolism
mtr00250  Alanine, aspartate and glutamate metabolism
mtr00260  Glycine, serine and threonine metabolism
mtr00620  Pyruvate metabolism
mtr00710  Carbon fixation by Calvin cycle
mtr00750  Vitamin B6 metabolism
mtr00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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