Entry
Name
ABC transporters - Mannheimia varigena USDA-ARS-USMARC-1388
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Mannheimia varigena USDA-ARS-USMARC-1388 [GN:
mve ]
Gene
X875_9450 Sulfate ABC transporter, periplasmic sulfate-binding protein [KO:K23163 ]
X875_9090 Binding-protein-dependent transport system inner membrane component [KO:K02011 ]
X875_15330 Spermidine/putrescine transport system permease protein PotC [KO:K11070 ]
X875_15320 Spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [KO:K11071 ]
X875_5190 Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
X875_16040 ABC-type transport system involved in resistance to organic solvent [KO:K07323 ]
X875_16050 ABC-type transport system involved in resistance to organic solvent [KO:K02067 ]
X875_20180 Monosaccharide ABC transporter substrate-binding protein, CUT2 [KO:K10439 ]
X875_160 L-arabinose transport system permease protein AraH [KO:K10538 ]
X875_19380 Periplasmic binding protein/LacI transcriptional regulator [KO:K17208 ]
X875_12360 ABC-type phosphate transport system substrate-binding protein [KO:K02040 ]
X875_10790 bifunctional amino acid-binding protein/DNA-binding protein [KO:K01999 ]
X875_15350 Binding-protein-dependent transport system inner membrane component [KO:K15582 ]
X875_9770 dipeptide ABC superfamily ATP-binding cassette transporter, binding protein [KO:K19226 ]
X875_17160 ABC-type Fe3+-hydroxamate transport system, periplasmic component [KO:K23227 ]
X875_3720 Zinc (Zn2+) ABC superfamily ATP binding cassette transporter, binding protein [KO:K09815 ]
X875_7730 High-affinity zinc uptake system membrane protein znuB [KO:K09816 ]
X875_4700 Lipoprotein-releasing system transmembrane protein lolC [KO:K09808 ]
X875_4720 Lipoprotein-releasing system transmembrane protein lolC [KO:K09808 ]
X875_4710 Lipoprotein releasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
X875_5810 Lipopolysaccharide export system permease protein lptF [KO:K07091 ]
X875_5820 Lipopolysaccharide export system permease protein lptG [KO:K11720 ]
X875_13590 microcin-H47 secretion/processing ATP-binding protein mchF [KO:K13409 ]
X875_10640 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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