KEGG   PATHWAY: naci00630
Entry
naci00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nisaea acidiphila
Class
Metabolism; Carbohydrate metabolism
Pathway map
naci00630  Glyoxylate and dicarboxylate metabolism
naci00630

Module
naci_M00012  Glyoxylate cycle [PATH:naci00630]
naci_M00621  Glycine cleavage system [PATH:naci00630]
naci_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:naci00630]
Other DBs
GO: 0046487 0043648
Organism
Nisaea acidiphila [GN:naci]
Gene
NUH88_07605  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NUH88_09540  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NUH88_13590  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
NUH88_14150  malate synthase G [KO:K01638] [EC:2.3.3.9]
NUH88_11580  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NUH88_01415  citrate synthase [KO:K01647] [EC:2.3.3.1]
NUH88_20030  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
NUH88_02595  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
NUH88_06190  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
NUH88_09935  thiolase family protein [KO:K00626] [EC:2.3.1.9]
NUH88_11930  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NUH88_14095  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NUH88_11935  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
NUH88_09395  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
NUH88_00770  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NUH88_01910  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
NUH88_14900  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
NUH88_13465  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
NUH88_13470  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
NUH88_06245  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
NUH88_06235  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
NUH88_06230  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
NUH88_10455  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
NUH88_12295  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
NUH88_00475  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
NUH88_05775  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
NUH88_14885  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
NUH88_19730  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
NUH88_06305  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
NUH88_11790  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
NUH88_19460  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
NUH88_00945  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NUH88_02420  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NUH88_15725  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NUH88_18295  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NUH88_18725  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NUH88_00735  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NUH88_15005  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NUH88_15015  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
NUH88_00550  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NUH88_11605  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NUH88_15010  gcvH; glycine cleavage system protein GcvH [KO:K02437]
NUH88_07855  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
NUH88_12610  NAD(P)-dependent oxidoreductase [KO:K00042] [EC:1.1.1.60]
NUH88_13560  glycerate kinase [KO:K11529] [EC:2.7.1.165]
NUH88_12350  fumarate hydratase [KO:K03779] [EC:4.2.1.32]
NUH88_12345  fumarate hydratase C-terminal domain-containing protein [KO:K03780] [EC:4.2.1.32]
NUH88_03485  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NUH88_16160  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NUH88_22130  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NUH88_08415  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
NUH88_16380  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
NUH88_01345  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
NUH88_10040  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
NUH88_16370  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
NUH88_01340  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
NUH88_10035  fdh3B; formate dehydrogenase FDH3 subunit beta [KO:K00124]
NUH88_16365  formate dehydrogenase [KO:K00124]
NUH88_10025  formate dehydrogenase subunit gamma [KO:K00127]
NUH88_16360  NAD(P)H-dependent oxidoreductase subunit E [KO:K00127]
NUH88_02710  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
naci00010  Glycolysis / Gluconeogenesis
naci00020  Citrate cycle (TCA cycle)
naci00030  Pentose phosphate pathway
naci00053  Ascorbate and aldarate metabolism
naci00071  Fatty acid degradation
naci00230  Purine metabolism
naci00250  Alanine, aspartate and glutamate metabolism
naci00260  Glycine, serine and threonine metabolism
naci00620  Pyruvate metabolism
naci00710  Carbon fixation by Calvin cycle
naci00750  Vitamin B6 metabolism
naci00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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