KEGG   PATHWAY: ndo00010
Entry
ndo00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Nonlabens dokdonensis
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
ndo00010  Glycolysis / Gluconeogenesis
ndo00010

Module
ndo_M00002  Glycolysis, core module involving three-carbon compounds [PATH:ndo00010]
ndo_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:ndo00010]
ndo_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ndo00010]
Other DBs
GO: 0006096 0006094
Organism
Nonlabens dokdonensis [GN:ndo]
Gene
DDD_0910  pgi; glucose-6-phosphate isomerase [KO:K01810] [EC:5.3.1.9]
DDD_3413  6-phosphofructokinase [KO:K00850] [EC:2.7.1.11]
DDD_1798  fbp; fructose-1,6-bisphosphatase [KO:K03841] [EC:3.1.3.11]
DDD_1846  fbaA; fructose-bisphosphate aldolase [KO:K01624] [EC:4.1.2.13]
DDD_0050  tpiA; triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
DDD_2575  gap; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
DDD_3412  gapA; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
DDD_0585  glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
DDD_1429  pgk; phosphoglycerate kinase [KO:K00927] [EC:2.7.2.3]
DDD_3316  putative phosphoglycerate mutase family protein [KO:K01834] [EC:5.4.2.11]
DDD_2044  phosphoglyceromutase [KO:K15633] [EC:5.4.2.12]
DDD_0513  eno; enolase [KO:K01689] [EC:4.2.1.11]
DDD_1276  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
DDD_1503  ppsA-1; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
DDD_2015  pdhA; pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase E1 component [KO:K00161] [EC:1.2.4.1]
DDD_1031  pdhB; pyruvate 2-oxoglutarate dehydrogenase beta subunit [KO:K00162] [EC:1.2.4.1]
DDD_2016  dihydrolipoyllysine-residue acetyltransferase [KO:K00627] [EC:2.3.1.12]
DDD_2157  lpdA2; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DDD_3568  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DDD_3297  zinc-type alcohol dehydrogenase [KO:K13953] [EC:1.1.1.1]
DDD_2147  aldehyde reductase [KO:K00002] [EC:1.1.1.2]
DDD_3221  cinnamyl-alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
DDD_2916  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
DDD_3172  chloroacetaldehyde dehydrogenase [KO:K00138] [EC:1.2.1.-]
DDD_0481  acsA; acyl-coenzyme A synthetases/AMP-(Fatty) acid ligase [KO:K01895] [EC:6.2.1.1]
DDD_3247  phosphomannomutase/phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
DDD_1064  pckA; phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
ndo00020  Citrate cycle (TCA cycle)
ndo00030  Pentose phosphate pathway
ndo00500  Starch and sucrose metabolism
ndo00620  Pyruvate metabolism
ndo00640  Propanoate metabolism
ndo00710  Carbon fixation by Calvin cycle
KO pathway
ko00010   
LinkDB

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