KEGG   PATHWAY: ngn00630
Entry
ngn00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Nonomuraea gerenzanensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
ngn00630  Glyoxylate and dicarboxylate metabolism
ngn00630

Module
ngn_M00012  Glyoxylate cycle [PATH:ngn00630]
ngn_M00621  Glycine cleavage system [PATH:ngn00630]
ngn_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ngn00630]
Other DBs
GO: 0046487 0043648
Organism
Nonomuraea gerenzanensis [GN:ngn]
Gene
LCN96_20785  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
LCN96_01835  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
LCN96_10410  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LCN96_13465  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LCN96_11925  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
LCN96_05535  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LCN96_40140  citrate synthase [KO:K01647] [EC:2.3.3.1]
LCN96_04305  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
LCN96_05500  citrate synthase [KO:K01647] [EC:2.3.3.1]
LCN96_32195  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
LCN96_41360  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
LCN96_45020  hypothetical protein [KO:K00626] [EC:2.3.1.9]
LCN96_48485  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
LCN96_48715  acetyl-CoA synthetase [KO:K00626] [EC:2.3.1.9]
LCN96_50335  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LCN96_04410  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LCN96_07200  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
LCN96_09100  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LCN96_11000  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LCN96_28095  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LCN96_44050  VOC family protein [KO:K05606] [EC:5.1.99.1]
LCN96_09095  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
LCN96_27240  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
LCN96_06005  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
LCN96_27250  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
LCN96_06230  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
LCN96_06225  acyl-CoA carboxylase subunit epsilon [KO:K27095]
LCN96_19740  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
LCN96_19745  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
LCN96_39850  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LCN96_11920  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LCN96_11915  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
LCN96_11910  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
LCN96_42015  catalase [KO:K03781] [EC:1.11.1.6]
LCN96_47185  catalase [KO:K03781] [EC:1.11.1.6]
LCN96_52495  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
LCN96_14135  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
LCN96_40300  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
LCN96_09440  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LCN96_16560  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LCN96_17335  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LCN96_18610  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LCN96_29895  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LCN96_40935  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LCN96_08935  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LCN96_17230  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LCN96_22835  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
LCN96_09420  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
LCN96_52985  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LCN96_15665  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LCN96_17420  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LCN96_09415  gcvH; glycine cleavage system protein GcvH [KO:K02437]
LCN96_12570  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
LCN96_48250  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
LCN96_12560  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
LCN96_37760  3-hydroxyisobutyrate dehydrogenase [KO:K00042] [EC:1.1.1.60]
LCN96_48245  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
LCN96_12565  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
LCN96_17960  glycerate kinase [KO:K00865] [EC:2.7.1.165]
LCN96_26095  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
LCN96_20590  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LCN96_26250  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LCN96_32000  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LCN96_48675  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
LCN96_36530  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
LCN96_13935  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
LCN96_33105  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
LCN96_33100  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
LCN96_36535  4Fe-4S dicluster domain-containing protein [KO:K00124]
LCN96_13945  4Fe-4S dicluster domain-containing protein [KO:K00124]
LCN96_31520  cytochrome b/b6 domain-containing protein [KO:K00127]
LCN96_43915  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
LCN96_05805  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
LCN96_13250  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
LCN96_12510  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ngn00010  Glycolysis / Gluconeogenesis
ngn00020  Citrate cycle (TCA cycle)
ngn00030  Pentose phosphate pathway
ngn00053  Ascorbate and aldarate metabolism
ngn00071  Fatty acid degradation
ngn00230  Purine metabolism
ngn00250  Alanine, aspartate and glutamate metabolism
ngn00260  Glycine, serine and threonine metabolism
ngn00620  Pyruvate metabolism
ngn00710  Carbon fixation by Calvin cycle
ngn00750  Vitamin B6 metabolism
ngn00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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