KEGG   PATHWAY: pfit00630
Entry
pfit00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas fitomaticsae
Class
Metabolism; Carbohydrate metabolism
Pathway map
pfit00630  Glyoxylate and dicarboxylate metabolism
pfit00630

Module
pfit_M00621  Glycine cleavage system [PATH:pfit00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas fitomaticsae [GN:pfit]
Gene
KJY40_18585  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
KJY40_15635  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
KJY40_23075  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
KJY40_25795  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
KJY40_27805  malate synthase G [KO:K01638] [EC:2.3.3.9]
KJY40_09380  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
KJY40_20035  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
KJY40_17765  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
KJY40_12190  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
KJY40_15625  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
KJY40_04370  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
KJY40_10045  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
KJY40_22240  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
KJY40_23380  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
KJY40_12965  VOC family protein [KO:K05606] [EC:5.1.99.1]
KJY40_12940  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
KJY40_12935  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
KJY40_12930  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
KJY40_13075  catalase [KO:K03781] [EC:1.11.1.6]
KJY40_18895  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
KJY40_26175  katB; catalase KatB [KO:K03781] [EC:1.11.1.6]
KJY40_27070  catalase [KO:K03781] [EC:1.11.1.6]
KJY40_01300  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
KJY40_13490  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
KJY40_20125  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
KJY40_05815  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
KJY40_25220  2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
KJY40_21740  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
KJY40_27440  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
KJY40_01430  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
KJY40_12110  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_12445  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_12530  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_15460  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_22905  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_28965  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_28975  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
KJY40_02695  glnA; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
KJY40_26130  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KJY40_27925  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
KJY40_23565  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
KJY40_29065  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
KJY40_23575  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
KJY40_29075  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
KJY40_18060  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
KJY40_00765  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
KJY40_09415  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
KJY40_23560  gcvH; glycine cleavage system protein GcvH [KO:K02437]
KJY40_29070  gcvH; glycine cleavage system protein GcvH [KO:K02437]
KJY40_09320  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
KJY40_09315  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
KJY40_09310  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
KJY40_15805  glycerate kinase [KO:K00865] [EC:2.7.1.165]
KJY40_09305  glycerate kinase [KO:K11529] [EC:2.7.1.165]
KJY40_17180  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
KJY40_12365  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
KJY40_23405  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
KJY40_15190  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
KJY40_15195  fdxH; formate dehydrogenase subunit beta [KO:K00124]
KJY40_15200  formate dehydrogenase subunit gamma [KO:K00127]
KJY40_23790  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KJY40_27900  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
KJY40_02810  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pfit00010  Glycolysis / Gluconeogenesis
pfit00020  Citrate cycle (TCA cycle)
pfit00030  Pentose phosphate pathway
pfit00053  Ascorbate and aldarate metabolism
pfit00071  Fatty acid degradation
pfit00230  Purine metabolism
pfit00250  Alanine, aspartate and glutamate metabolism
pfit00260  Glycine, serine and threonine metabolism
pfit00620  Pyruvate metabolism
pfit00710  Carbon fixation by Calvin cycle
pfit00750  Vitamin B6 metabolism
pfit00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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