KEGG   PATHWAY: pgu04011
Entry
pgu04011                    Pathway                                
Name
MAPK signaling pathway - yeast - Meyerozyma guilliermondii
Description
The S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third (Hog1) is necessary for survival under hyperosmotic conditions. A fourth (Slt2/Mpk1) is required for repair of injuries to the cell wall. As in mammalian cells, these pathways consist of a conserved module in which three kinases phosphorylate each other in sequence. The MAPK is phosphorylated by the MAPK/ERK kinase (MAPKK/MEK), which is itself phosphorylated by a MEK kinase (MAPKKK/MEKK).
Class
Environmental Information Processing; Signal transduction
Pathway map
pgu04011  MAPK signaling pathway - yeast
pgu04011

Other DBs
GO: 0000165
Organism
Meyerozyma guilliermondii [GN:pgu]
Gene
PGUG_01971  hypothetical protein [KO:K11213]
PGUG_01567  hypothetical protein [KO:K04627]
PGUG_01558  hypothetical protein [KO:K02218] [EC:2.7.11.1]
PGUG_02011  hypothetical protein [KO:K02218] [EC:2.7.11.1]
PGUG_01556  hypothetical protein [KO:K10591] [EC:2.3.2.26]
PGUG_00500  hypothetical protein [KO:K19860]
PGUG_03852  hypothetical protein [KO:K04536]
PGUG_05409  hypothetical protein [KO:K19838]
PGUG_03379  hypothetical protein [KO:K11236]
PGUG_04396  cell division control protein 42 [KO:K04393]
PGUG_05229  hypothetical protein [KO:K19839]
PGUG_04047  hypothetical protein [KO:K19840]
PGUG_01628  hypothetical protein [KO:K11237]
PGUG_02822  hypothetical protein [KO:K04409] [EC:2.7.11.1]
PGUG_01780  hypothetical protein [KO:K19833] [EC:2.7.11.1]
PGUG_03629  hypothetical protein [KO:K11238]
PGUG_03686  hypothetical protein [KO:K11228] [EC:2.7.11.25]
PGUG_00656  hypothetical protein [KO:K19841]
PGUG_04334  hypothetical protein [KO:K11239]
PGUG_03840  hypothetical protein [KO:K11226] [EC:2.7.12.2]
PGUG_03489  extracellular signal-regulated kinase 1 [KO:K04371] [EC:2.7.11.24]
PGUG_02967  hypothetical protein [KO:K19806] [EC:3.1.3.48]
PGUG_04529  hypothetical protein [KO:K19806] [EC:3.1.3.48]
PGUG_05117  hypothetical protein [KO:K11240] [EC:3.1.3.48]
PGUG_03108  hypothetical protein [KO:K11215]
PGUG_00395  hypothetical protein [KO:K12412]
PGUG_00954  hypothetical protein [KO:K06652]
PGUG_04785  cell division control protein 28 [KO:K04563] [EC:2.7.11.22]
PGUG_01691  hypothetical protein [KO:K11244]
PGUG_05106  hypothetical protein [KO:K11244]
PGUG_02924  hypothetical protein [KO:K19842]
PGUG_02145  hypothetical protein [KO:K19843]
PGUG_03472  hypothetical protein [KO:K00888] [EC:2.7.1.67]
PGUG_03452  hypothetical protein [KO:K00889] [EC:2.7.1.68]
PGUG_01737  protein RHO1 [KO:K04513]
PGUG_00158  hypothetical protein [KO:K19844]
PGUG_04306  hypothetical protein [KO:K19845]
PGUG_01247  hypothetical protein [KO:K17971]
PGUG_04383  hypothetical protein [KO:K02677] [EC:2.7.11.13]
PGUG_02746  hypothetical protein [KO:K06276] [EC:2.7.11.1]
PGUG_02948  hypothetical protein [KO:K06276] [EC:2.7.11.1]
PGUG_03900  hypothetical protein [KO:K11229] [EC:2.7.11.25]
PGUG_00992  hypothetical protein [KO:K08294] [EC:2.7.12.2]
PGUG_03224  hypothetical protein [KO:K19846]
PGUG_01253  similar to MpkA [KO:K04464] [EC:2.7.11.24]
PGUG_02571  hypothetical protein [KO:K09265]
PGUG_01168  similar to beta-1,3-glucan synthase [KO:K00706] [EC:2.4.1.34]
PGUG_00803  hypothetical protein [KO:K00706] [EC:2.4.1.34]
PGUG_02097  hypothetical protein [KO:K00706] [EC:2.4.1.34]
PGUG_05134  hypothetical protein [KO:K15174]
PGUG_00771  hypothetical protein [KO:K06649]
PGUG_03320  hypothetical protein [KO:K06648]
PGUG_03523  hypothetical protein [KO:K02555] [EC:3.1.3.48]
PGUG_04952  hypothetical protein [KO:K23469]
PGUG_05794  hypothetical protein [KO:K11246]
PGUG_01283  hypothetical protein [KO:K19850]
PGUG_03258  hypothetical protein [KO:K11231] [EC:2.7.13.3]
PGUG_05889  hypothetical protein [KO:K11232]
PGUG_01054  hypothetical protein [KO:K11233]
PGUG_03774  hypothetical protein [KO:K11230] [EC:2.7.11.25]
PGUG_04163  hypothetical protein [KO:K11227] [EC:2.7.12.2]
PGUG_05033  mitogen-activated protein kinase HOG1 [KO:K04441] [EC:2.7.11.24]
PGUG_05844  hypothetical protein [KO:K19704] [EC:3.1.3.16]
PGUG_01519  hypothetical protein [KO:K00006] [EC:1.1.1.8]
PGUG_05498  hypothetical protein [KO:K00006] [EC:1.1.1.8]
PGUG_01635  hypothetical protein [KO:K09468]
PGUG_05581  hypothetical protein [KO:K03781] [EC:1.11.1.6]
PGUG_01850  peroxisomal catalase [KO:K03781] [EC:1.11.1.6]
PGUG_04717  hypothetical protein [KO:K09051]
PGUG_02263  hypothetical protein [KO:K06665]
PGUG_01096  hypothetical protein [KO:K06666]
PGUG_05107  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_03923  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_03246  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_03261  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_05714  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_05690  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_05800  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_05692  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_04552  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_02054  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_04595  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_05159  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_04892  hypothetical protein [KO:K17741] [EC:1.1.1.283]
PGUG_04386  hypothetical protein [KO:K02515] [EC:2.7.11.-]
PGUG_02814  similar to protein kinase [KO:K02516] [EC:2.1.1.320]
PGUG_05112  hypothetical protein [KO:K03114] [EC:2.7.11.1]
PGUG_01925  hypothetical protein [KO:K06009] [EC:3.4.23.41]
PGUG_04326  protein BMH2 [KO:K06630]
PGUG_04378  hypothetical protein [KO:K09448]
Reference
PMID:15690603
  Authors
Bardwell L
  Title
A walk-through of the yeast mating pheromone response pathway.
  Journal
Peptides 26:339-50 (2005)
DOI:10.1016/j.peptides.2004.10.002
Reference
PMID:15944456
  Authors
Levin DE
  Title
Cell wall integrity signaling in Saccharomyces cerevisiae.
  Journal
Microbiol Mol Biol Rev 69:262-91 (2005)
DOI:10.1128/MMBR.69.2.262-291.2005
Reference
PMID:22174182
  Authors
Levin DE
  Title
Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.
  Journal
Genetics 189:1145-75 (2011)
DOI:10.1534/genetics.111.128264
Reference
PMID:17875410
  Authors
Hohmann S, Krantz M, Nordlander B
  Title
Yeast osmoregulation.
  Journal
Methods Enzymol 428:29-45 (2007)
DOI:10.1016/S0076-6879(07)28002-4
Reference
PMID:23028184
  Authors
Saito H, Posas F
  Title
Response to hyperosmotic stress.
  Journal
Genetics 192:289-318 (2012)
DOI:10.1534/genetics.112.140863
Reference
PMID:22219507
  Authors
Cullen PJ, Sprague GF Jr
  Title
The regulation of filamentous growth in yeast.
  Journal
Genetics 190:23-49 (2012)
DOI:10.1534/genetics.111.127456
Reference
PMID:9841672
  Authors
Gustin MC, Albertyn J, Alexander M, Davenport K
  Title
MAP kinase pathways in the yeast Saccharomyces cerevisiae.
  Journal
Microbiol Mol Biol Rev 62:1264-300 (1998)
Reference
PMID:17604854
  Authors
Chen RE, Thorner J
  Title
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1773:1311-40 (2007)
DOI:10.1016/j.bbamcr.2007.05.003
KO pathway
ko04011   
LinkDB

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