KEGG   PATHWAY: plep00630
Entry
plep00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Plectropomus leopardus (leopard coralgrouper)
Class
Metabolism; Carbohydrate metabolism
Pathway map
plep00630  Glyoxylate and dicarboxylate metabolism
plep00630

Module
plep_M00621  Glycine cleavage system [PATH:plep00630]
plep_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:plep00630]
Other DBs
GO: 0046487 0043648
Organism
Plectropomus leopardus (leopard coralgrouper) [GN:plep]
Gene
121946625  acss2; acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [KO:K01895] [EC:6.2.1.1]
121955150  acss1; acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
121951569  acss2l; acyl-CoA synthetase short chain family member 2 like [KO:K01895] [EC:6.2.1.1]
121954839  mdh1ab; malate dehydrogenase 1Ab, NAD (soluble) [KO:K00025] [EC:1.1.1.37]
121945612  mdh2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
121946505  cs; citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
121958458  aco2; aconitate hydratase, mitochondrial [KO:K01681] [EC:4.2.1.3]
121956104  aconitate hydratase, mitochondrial-like [KO:K01681] [EC:4.2.1.3]
121962361  aco1; cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
121952834  acat1; acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
121955839  acat2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
121948299  mcee; methylmalonyl-CoA epimerase, mitochondrial isoform X1 [KO:K05606] [EC:5.1.99.1]
121954916  pcca; propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
121953513  pccb; propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
121955617  mmut; methylmalonyl-CoA mutase, mitochondrial [KO:K01847] [EC:5.4.99.2]
121967011  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
121949279  hao2; hydroxyacid oxidase 2 isoform X1 [KO:K11517] [EC:1.1.3.15]
121957056  LOW QUALITY PROTEIN: hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
121950053  cat; LOW QUALITY PROTEIN: catalase [KO:K03781] [EC:1.11.1.6]
121942446  grhprb; glyoxylate reductase/hydroxypyruvate reductase b [KO:K00049] [EC:1.1.1.79 1.1.1.81]
121948408  grhpra; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
121958887  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
121941140  agxta; alanine--glyoxylate and serine--pyruvate aminotransferase a [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
121951646  agxtb; alanine--glyoxylate and serine--pyruvate aminotransferase b [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
121941175  glulb; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
121959432  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
121956836  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
121951536  glula; glutamate-ammonia ligase (glutamine synthase) a [KO:K01915] [EC:6.3.1.2]
121939476  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
121939477  glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
121940572  serine hydroxymethyltransferase, cytosolic-like [KO:K00600] [EC:2.1.2.1]
121947535  LOW QUALITY PROTEIN: serine hydroxymethyltransferase, mitochondrial-like [KO:K00600] [EC:2.1.2.1]
121956686  shmt1; LOW QUALITY PROTEIN: serine hydroxymethyltransferase, cytosolic [KO:K00600] [EC:2.1.2.1]
121957171  shmt2; serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
121944847  gldc; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
121946991  amt; LOW QUALITY PROTEIN: aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
121956883  dldh; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
121944525  gcshb; glycine cleavage system protein H (aminomethyl carrier), b [KO:K02437]
121950673  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
121941179  hyi; putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
121958055  glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
121941781  afmid; kynurenine formamidase isoform X1 [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
plep00010  Glycolysis / Gluconeogenesis
plep00020  Citrate cycle (TCA cycle)
plep00030  Pentose phosphate pathway
plep00053  Ascorbate and aldarate metabolism
plep00071  Fatty acid degradation
plep00230  Purine metabolism
plep00250  Alanine, aspartate and glutamate metabolism
plep00260  Glycine, serine and threonine metabolism
plep00620  Pyruvate metabolism
plep00750  Vitamin B6 metabolism
plep00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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