KEGG   PATHWAY: qsu00999
Entry
qsu00999                    Pathway                                
Name
Biosynthesis of various plant secondary metabolites - Quercus suber (cork oak)
  Including
Crocin biosynthesis, Ginsenoside biosynthesis, Saponin adjuvant biosynthesis, Cannabidiol biosynthesis, Mugineic acid biosynthesis, Pentagalloylglucose biosynthesis, Benzoxazinoid biosynthesis, Gramine biosynthesis, Coumarin biosynthesis, Furanocoumarin biosynthesis, Hordatine biosynthesis, Podophyllotoxin biosynthesis
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
qsu00999  Biosynthesis of various plant secondary metabolites
qsu00999

Organism
Quercus suber (cork oak) [GN:qsu]
Gene
111984348  beta-amyrin synthase isoform X1 [KO:K15813] [EC:5.4.99.39]
111993359  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112028926  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112029397  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112029584  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112029585  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111999310  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112029583  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111984351  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111984352  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111984353  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111984354  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111988686  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
112000640  beta-amyrin synthase-like [KO:K15813] [EC:5.4.99.39]
111984580  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112003765  beta-amyrin 28-oxidase-like isoform X1 [KO:K20667] [EC:1.14.14.126]
112009785  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112012433  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
111994391  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
111984350  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
111984387  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112023020  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
111996765  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112007351  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112007353  beta-amyrin 28-oxidase-like [KO:K20667] [EC:1.14.14.126]
112005507  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
112020243  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
111997747  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
112025941  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
112024641  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
112032159  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
111986344  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
112028738  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
112030430  non-functional NADPH-dependent codeinone reductase 2-like [KO:K22374] [EC:1.1.1.285]
112033836  non-functional NADPH-dependent codeinone reductase 2-like [KO:K22374] [EC:1.1.1.285]
112010474  methylecgonone reductase-like [KO:K22374] [EC:1.1.1.285]
112003968  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like isoform X1 [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112010936  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like isoform X1 [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112012724  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like isoform X1 [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112030015  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112030016  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112030050  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112030053  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112025792  bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic-like [KO:K13832] [EC:4.2.1.10 1.1.1.25]
112015185  gallate 1-beta-glucosyltransferase [KO:K23279] [EC:2.4.1.136]
112006422  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
112005967  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
111994635  beta-glucosidase 11-like isoform X1 [KO:K01188] [EC:3.2.1.21]
111990919  beta-glucosidase 40 [KO:K01188] [EC:3.2.1.21]
111996802  beta-glucosidase 42-like isoform X1 [KO:K01188] [EC:3.2.1.21]
111996803  beta-glucosidase 42-like isoform X1 [KO:K01188] [EC:3.2.1.21]
112021752  beta-glucosidase 42-like [KO:K01188] [EC:3.2.1.21]
112035860  beta-glucosidase 42-like [KO:K01188] [EC:3.2.1.21]
111994637  beta-glucosidase 11-like [KO:K01188] [EC:3.2.1.21]
111994633  beta-glucosidase 11-like isoform X1 [KO:K01188] [EC:3.2.1.21]
111994641  beta-glucosidase 11-like [KO:K01188] [EC:3.2.1.21]
112025582  putative beta-glucosidase 41 isoform X1 [KO:K01188] [EC:3.2.1.21]
111988203  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
111988802  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
111997528  beta-glucosidase 12-like isoform X1 [KO:K01188] [EC:3.2.1.21]
112002104  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
112011068  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
112025375  beta-glucosidase 12-like [KO:K01188] [EC:3.2.1.21]
112010098  beta-glucosidase 24-like [KO:K01188] [EC:3.2.1.21]
112010082  beta-glucosidase 24-like [KO:K01188] [EC:3.2.1.21]
112003897  uncharacterized protein LOC112003897 isoform X1 [KO:K05349] [EC:3.2.1.21]
112003321  uncharacterized protein LOC112003321 [KO:K05349] [EC:3.2.1.21]
112003323  uncharacterized protein LOC112003323 [KO:K05349] [EC:3.2.1.21]
112018098  uncharacterized protein LOC112018098 [KO:K05349] [EC:3.2.1.21]
111996302  uncharacterized protein LOC111996302 [KO:K05349] [EC:3.2.1.21]
111996303  uncharacterized protein LOC111996303 [KO:K05349] [EC:3.2.1.21]
111996304  uncharacterized protein LOC111996304 [KO:K05349] [EC:3.2.1.21]
111996306  uncharacterized protein LOC111996306 [KO:K05349] [EC:3.2.1.21]
111998403  uncharacterized protein LOC111998403 [KO:K05349] [EC:3.2.1.21]
111998404  uncharacterized protein LOC111998404 [KO:K05349] [EC:3.2.1.21]
112003309  uncharacterized protein LOC112003309 [KO:K05349] [EC:3.2.1.21]
112026966  uncharacterized protein LOC112026966 [KO:K05349] [EC:3.2.1.21]
112040661  beta-glucosidase 18-like isoform X1 [KO:K05350] [EC:3.2.1.21]
112010864  beta-glucosidase 46-like isoform X1 [KO:K05350] [EC:3.2.1.21]
112010866  beta-glucosidase 46-like isoform X1 [KO:K05350] [EC:3.2.1.21]
112033924  beta-glucosidase 46-like [KO:K05350] [EC:3.2.1.21]
112033931  beta-glucosidase 46-like [KO:K05350] [EC:3.2.1.21]
112037100  beta-glucosidase 44-like isoform X1 [KO:K05350] [EC:3.2.1.21]
112037103  beta-glucosidase 44-like [KO:K05350] [EC:3.2.1.21]
112032284  feruloyl CoA ortho-hydroxylase 2-like [KO:K06892] [EC:1.14.11.61]
112032285  feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]
112032288  feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]
111987312  feruloyl CoA ortho-hydroxylase 1-like isoform X1 [KO:K06892] [EC:1.14.11.61]
112010742  feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]
111991061  LOW QUALITY PROTEIN: feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]
111991086  feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]
112009979  feruloyl CoA ortho-hydroxylase 1-like [KO:K23145] [EC:1.14.11.60]
111986809  feruloyl CoA ortho-hydroxylase 1-like [KO:K23145] [EC:1.14.11.60]
112004233  cytochrome P450 82C4-like [KO:K23136] [EC:1.14.14.164]
112024377  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112024393  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112025895  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112024957  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112025005  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112039853  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
111990322  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112007061  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
111997961  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
111986676  scopoletin glucosyltransferase-like isoform X1 [KO:K23260] [EC:2.4.1.128]
111997959  scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]
112023934  bifunctional pinoresinol-lariciresinol reductase-like isoform X1 [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
112023936  bifunctional pinoresinol-lariciresinol reductase 2-like isoform X1 [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
112015239  isoflavone reductase homolog [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
112001516  isoflavone reductase homolog [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
112001517  isoflavone reductase homolog [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
112001518  isoflavone reductase homolog [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]
Compound
C00019  S-Adenosyl-L-methionine
C00024  Acetyl-CoA
C00036  Oxaloacetate
C00049  L-Aspartate
C00073  L-Methionine
C00074  Phosphoenolpyruvate
C00078  L-Tryptophan
C00079  L-Phenylalanine
C00082  L-Tyrosine
C00083  Malonyl-CoA
C00108  Anthranilate
C00179  Agmatine
C00223  p-Coumaroyl-CoA
C00251  Chorismate
C00254  Prephenate
C00323  Caffeoyl-CoA
C00353  Geranylgeranyl diphosphate
C00406  Feruloyl-CoA
C00423  trans-Cinnamate
C00448  trans,trans-Farnesyl diphosphate
C00463  Indole
C00493  Shikimate
C00590  Coniferyl alcohol
C00751  Squalene
C00758  Bergaptol
C00841  Xanthotoxol
C01054  (S)-2,3-Epoxysqualene
C01158  1-O-Galloyl-beta-D-glucose
C01198  3-(2-Hydroxyphenyl)propanoate
C01424  Gallate
C01527  Scopolin
C01557  Bergapten
C01752  Scopoletin
C01772  trans-2-Hydroxycinnamate
C01864  Xanthotoxin
C02162  Isopimpinellin
C02274  Dihydrocoumarin
C02637  3-Dehydroshikimate
C02951  5-Hydroxyxanthotoxin
C03506  Indoleglycerol phosphate
C04498  p-Coumaroylagmatine
C04576  Pentagalloylglucose
C04831  DIMBOA-glucoside
C05158  trans-beta-D-Glucosyl-2-hydroxycinnamate
C05324  Nicotianamine
C05366  (+)-Pinoresinol
C05838  cis-2-Hydroxycinnamate
C05839  cis-beta-D-Glucosyl-2-hydroxycinnamate
C05851  Coumarin
C06098  Zeaxanthin
C06972  Dronabinol
C07578  Cannabidiol
C08304  Gramine
C08307  Hordatine A
C08308  Hordatine B
C08588  Crocetin
C08589  Crocin
C08616  beta-Amyrin
C08942  Echinocystic acid
C08946  Ginsenoside Rg1
C08972  Quillaic acid
C09060  Angelicin
C09263  Esculetin
C09265  Fraxetin
C09276  Marmesin
C09305  Psoralen
C09311  Scoparone
C09315  Umbelliferone
C10556  Deoxypodophyllotoxin
C10557  Dihydroanhydropodorhizol
C10646  Lariciresinol
C10682  Matairesinol
C10784  Cannabidiolic acid
C10874  Podophyllotoxin
C11130  3-Hydroxyindolin-2-one
C12312  Indolin-2-one
C15485  2'-Deoxymugineic acid
C15486  3''-Deamino-3''-oxonicotianamine
C15500  Mugineic acid
C15501  3-Epihydroxymugineic acid
C15502  3-Epihydroxy-2'-deoxymugineic acid
C15769  HBOA
C15770  DIBOA
C15772  DIBOA-glucoside
C17055  Picrocrocin
C17062  Safranal
C17148  Oleanolic acid
C17513  trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester
C18062  TRIBOA-glucoside
C18079  Isoscopoletin
C18080  Osthenol
C18083  Demethylsuberosin
C18167  Secoisolariciresinol
C18325  Feruloylagmatine
C19707  (+)-Columbianetin
C19730  Crocetin dialdehyde
C19731  (3S)-3-Hydroxycyclocitral
C19829  Dammarenediol-II
C19867  beta-D-Glucosyl crocetin
C19868  Bis(beta-D-glucosyl) crocetin
C19869  beta-D-Gentiobiosyl crocetin
C20406  Cannabigerolate
C20413  3,5,7-Trioxododecanoyl-CoA
C20417  2,4-Dihydroxy-6-pentylbenzoate
C20454  (-)-Lariciresinol
C20455  (-)-Pinoresinol
C20456  (+)-Secoisolariciresinol
C20713  Ginsenoside Rb1
C20715  Protopanaxadiol
C20716  Protopanaxatriol
C20725  Ginsenoside Rd
C20778  Ginsenoside Rg3
C20779  Ginsenoside F2
C20780  Ginsenoside F1
C20894  beta-Citraurin
C21183  Bursehernin
C21184  (-)-5'-Demethylyatein
C21191  Pluviatolide
C21459  6-Hydroxyferuloyl-CoA
C21601  3-(Aminomethyl)indole
C21602  (1H-Indol-3-yl)-N-methylmethanamine
C21903  Delta9-Tetrahydrocannabinolate
C22007  Sideretin
C22070  2,4-Dihydroxycinnamoyl-CoA
C22127  Ginsenoside C-K
C22128  (20S)-Ginsenoside Rh2
C22129  Ginsenoside Rh1
C22152  Bergamottin
C22153  Epoxybergamottin
C22156  6',7'-Dihydroxybergamottin
C22438  3,5-Dehydroshikimate
C22444  5,8-Dihydroxypsoralen
C22445  8-Hydroxybergapten
C22452  6,7,8-Trihydroxycoumarin
C22652  Quillaic acid 3-O-beta-D-glucuronide
C22653  Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide
C22654  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide
C22655  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide
C22656  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside
C22657  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside
C22658  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22659  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22660  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22661  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22662  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22663  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22664  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22665  Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside
C22666  Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide 28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-(beta-D-glucosyl-1,3)-alpha-L-rhamnosyl-1,2-(alpha-L-rhamnosyl-1,3)-4-O-acetyl-beta-D-fucoside
Reference
  Authors
Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H
  Title
UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides.
  Journal
FEBS Lett 586:1055-61 (2012)
DOI:10.1016/j.febslet.2012.03.003
Reference
  Authors
Taura F, Sirikantaramas S, Shoyama Y, Yoshikai K, Shoyama Y, Morimoto S
  Title
Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa.
  Journal
FEBS Lett 581:2929-34 (2007)
DOI:10.1016/j.febslet.2007.05.043
Reference
PMID:9952442
  Authors
Higuchi K, Suzuki K, Nakanishi H, Yamaguchi H, Nishizawa NK, Mori S
  Title
Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores.
  Journal
Plant Physiol 119:471-80 (1999)
DOI:10.1104/pp.119.2.471
Reference
PMID:7622460
  Authors
Ma JF, Shinada T, Matsuda C, Nomoto K
  Title
Biosynthesis of phytosiderophores, mugineic acids, associated with methionine cycling.
  Journal
J Biol Chem 270:16549-54 (1995)
DOI:10.1074/jbc.270.28.16549
Reference
  Authors
Tahara K, Nishiguchi M, Funke E, Miyazawa SI, Miyama T, Milkowski C
  Title
Dehydroquinate dehydratase/shikimate dehydrogenases involved in gallate biosynthesis of the aluminum-tolerant tree species Eucalyptus camaldulensis.
  Journal
Planta 253:3 (2020)
DOI:10.1007/s00425-020-03516-w
Reference
  Authors
Dugrand-Judek A, Olry A, Hehn A, Costantino G, Ollitrault P, Froelicher Y, Bourgaud F.
  Title
The Distribution of Coumarins and Furanocoumarins in Citrus Species Closely Matches Citrus Phylogeny and Reflects the Organization of Biosynthetic Pathways.
  Journal
PLoS One 10:e0142757 (2015)
DOI:10.1371/journal.pone.0142757
Reference
  Authors
Hehmann M, Lukacin R, Ekiert H, Matern U
  Title
Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.
  Journal
Eur J Biochem 271:932-40 (2004)
DOI:10.1111/j.1432-1033.2004.03995.x
Reference
  Authors
Lau W, Sattely ES
  Title
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.
  Journal
Science 349:1224-8 (2015)
DOI:10.1126/science.aac7202
Reference
  Authors
Reed J, Orme A, El-Demerdash A, Owen C, Martin LBB, Misra RC, Kikuchi S, Rejzek M, Martin AC, Harkess A, Leebens-Mack J, Louveau T, Stephenson MJ, Osbourn A.
  Title
Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree.
  Journal
Science 379:1252-1264 (2023)
DOI:10.1126/science.adf3727
Related
pathway
qsu00010  Glycolysis / Gluconeogenesis
qsu00020  Citrate cycle (TCA cycle)
qsu00270  Cysteine and methionine metabolism
qsu00400  Phenylalanine, tyrosine and tryptophan biosynthesis
qsu00900  Terpenoid backbone biosynthesis
qsu00940  Phenylpropanoid biosynthesis
KO pathway
ko00999   
LinkDB

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