KEGG   PATHWAY: rn00770
Entry
rn00770                     Pathway                                
Name
Pantothenate and CoA biosynthesis
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
rn00770  Pantothenate and CoA biosynthesis
rn00770

Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:rn00770]
M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:rn00770]
M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:rn00770]
M00120  Coenzyme A biosynthesis, pantothenate => CoA [PATH:rn00770]
M00913  Pantothenate biosynthesis, 2-oxoisovalerate/spermine => pantothenate [PATH:rn00770]
M00914  Coenzyme A biosynthesis, archaea, 2-oxoisovalerate => 4-phosphopantoate => CoA [PATH:rn00770]
Other DBs
GO: 0015940 0015937
Reaction
R00130  ATP:dephospho-CoA 3'-phosphotransferase
R00226  pyruvate:pyruvate acetaldehydetransferase (decarboxylating); (S)-2-acetolactate pyruvate-lyase (carboxylating)
R00489  L-aspartate 1-carboxy-lyase (beta-alanine-forming)
R00904  3-aminopropanal:NAD+ oxidoreductase
R00905  3-ureidopropanoate amidohydrolase
R00977  5,6-dihydrouracil:NAD+ oxidoreductase
R00978  5,6-dihydrouracil:NADP+ oxidoreductase
R01211  (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)
R01214  L-valine:2-oxoglutarate aminotransferase
R01226  5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase
R01623  [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase
R01625  CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase
R02269  5,6-dihydrouracil amidohydrolase
R02471  
R02472  (R)-pantoate:NADP+ 2-oxidoreductase
R02473  (R)-pantoate:beta-alanine ligase (AMP-forming)
R02474  pantothenate amidohydrolase
R02971  ATP:pantothenate 4'-phosphotransferase
R02972  N-((R)-pantothenoyl)-L-cysteine carboxy-lyase
R02973  (R)-pantetheine amidohydrolase
R03018  ATP:pantothenate 4'-phosphotransferase
R03035  ATP:pantetheine-4'-phosphate adenylyltransferase
R03036  dephospho-CoA nucleotidohydrolase
R03198  (R)-4-dehydropantoate:NAD+ 4-oxidoreductase
R03269  N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase
R03927  
R04230  (R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing)
R04231  (R)-4'-phosphopantothenate:L-cysteine ligase
R04391  ATP:pantothenate 4'-phosphotransferase
R04439  (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
R04441  (R)-2,3-dihydroxy-3-methylbutanoate hydro-lyase
R09076  spermidine:oxygen oxidoreductase (spermidine-forming)
R09378  ATP:(R)-pantoate 4-phosphotransferase
R09379  (R)-4-phosphopantoate:beta-alanine ligase (AMP-forming)
R12608  GTP:3'-dephospho-CoA 3'-phosphotransferase
Compound
C00010  CoA
C00022  Pyruvate
C00049  L-Aspartate
C00054  Adenosine 3',5'-bisphosphate
C00097  L-Cysteine
C00099  beta-Alanine
C00106  Uracil
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00229  Acyl-carrier protein
C00429  5,6-Dihydrouracil
C00522  (R)-Pantoate
C00750  Spermine
C00831  Pantetheine
C00864  Pantothenate
C00882  Dephospho-CoA
C00966  2-Dehydropantoate
C01053  (R)-4-Dehydropantoate
C01088  (R)-3,3-Dimethylmalate
C01134  Pantetheine 4'-phosphate
C02642  3-Ureidopropionate
C03492  D-4'-Phosphopantothenate
C03688  Apo-[acyl-carrier protein]
C04079  N-((R)-Pantothenoyl)-L-cysteine
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04352  (R)-4'-Phosphopantothenoyl-L-cysteine
C05665  3-Aminopropanal
C05944  Pantothenol
C06010  (S)-2-Acetolactate
C18911  (R)-4-Phosphopantoate
Related
pathway
rn00010  Glycolysis / Gluconeogenesis
rn00240  Pyrimidine metabolism
rn00250  Alanine, aspartate and glutamate metabolism
rn00270  Cysteine and methionine metabolism
rn00330  Arginine and proline metabolism
rn00410  beta-Alanine metabolism
rn00640  Propanoate metabolism
KO pathway
ko00770   

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