KEGG   PATHWAY: ko00770
Entry
ko00770                     Pathway                                
Name
Pantothenate and CoA biosynthesis
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ko00770  Pantothenate and CoA biosynthesis
ko00770

Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ko00770]
M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:ko00770]
M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:ko00770]
M00120  Coenzyme A biosynthesis, pantothenate => CoA [PATH:ko00770]
M00913  Pantothenate biosynthesis, 2-oxoisovalerate/spermine => pantothenate [PATH:ko00770]
M00914  Coenzyme A biosynthesis, archaea, 2-oxoisovalerate => 4-phosphopantoate => CoA [PATH:ko00770]
Other DBs
GO: 0015940 0015937
Orthology
K00053  ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
K00077  panE, apbA; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
K00128  ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00207  DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
K00606  panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
K00826  E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]
K00859  coaE; dephospho-CoA kinase [EC:2.7.1.24]
K00867  coaA; type I pantothenate kinase [EC:2.7.1.33]
K00954  E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
K00997  acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
K01431  UPB1, pydC; beta-ureidopropionase [EC:3.5.1.6]
K01464  DPYS, dht, hydA; dihydropyrimidinase [EC:3.5.2.2]
K01513  ENPP1_3, CD203; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01579  panD; aspartate 1-decarboxylase [EC:4.1.1.11]
K01598  PPCDC, coaC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]
K01652  E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]
K01687  ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
K01918  panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
K01922  PPCS, COAB; phosphopantothenate---cysteine ligase (ATP) [EC:6.3.2.51]
K01947  birA-coaX; biotin---[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
K02201  E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
K03525  coaX; type III pantothenate kinase [EC:2.7.1.33]
K04765  mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
K06016  pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
K06133  LYS5, acpT; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]
K06982  pok; pantoate kinase [EC:2.7.1.169]
K08069  VNN; pantetheine hydrolase [EC:3.5.1.92]
K08682  acpH; acyl carrier protein phosphodiesterase [EC:3.1.4.14]
K09680  PANK1_2_3, CAB1, coaW; type II pantothenate kinase [EC:2.7.1.33]
K09722  K09722, pps; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
K09735  dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
K11258  ilvM; acetolactate synthase II small subunit [EC:2.2.1.6]
K13038  coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
K13367  FMS1; polyamine oxidase [EC:1.5.3.17]
K13799  panC-cmk; pantoate ligase / CMP/dCMP kinase [EC:6.3.2.1 2.7.4.25]
K17722  preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
K17723  preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
K17839  PAO4, PAO3, PAO2; polyamine oxidase [EC:1.5.3.17 1.5.3.-]
K18933  mfnA, adc; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
K18966  GADL1, CSAD; sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11]
K21977  coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
K24263  panG; 2-dehydropantoate 2-reductase
K24264  panP; aspartate 1-decarboxylase
Compound
C00010  CoA
C00022  Pyruvate
C00049  L-Aspartate
C00054  Adenosine 3',5'-bisphosphate
C00097  L-Cysteine
C00099  beta-Alanine
C00106  Uracil
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00229  Acyl-carrier protein
C00429  5,6-Dihydrouracil
C00522  (R)-Pantoate
C00750  Spermine
C00831  Pantetheine
C00864  Pantothenate
C00882  Dephospho-CoA
C00966  2-Dehydropantoate
C01053  (R)-4-Dehydropantoate
C01088  (R)-3,3-Dimethylmalate
C01134  Pantetheine 4'-phosphate
C02642  3-Ureidopropionate
C03492  D-4'-Phosphopantothenate
C03688  Apo-[acyl-carrier protein]
C04079  N-((R)-Pantothenoyl)-L-cysteine
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04352  (R)-4'-Phosphopantothenoyl-L-cysteine
C05665  3-Aminopropanal
C05944  Pantothenol
C06010  (S)-2-Acetolactate
C18911  (R)-4-Phosphopantoate
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00240  Pyrimidine metabolism
ko00250  Alanine, aspartate and glutamate metabolism
ko00270  Cysteine and methionine metabolism
ko00330  Arginine and proline metabolism
ko00410  beta-Alanine metabolism
ko00640  Propanoate metabolism

DBGET integrated database retrieval system