KEGG   PATHWAY: saov00630
Entry
saov00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces aureoverticillatus
Class
Metabolism; Carbohydrate metabolism
Pathway map
saov00630  Glyoxylate and dicarboxylate metabolism
saov00630

Module
saov_M00012  Glyoxylate cycle [PATH:saov00630]
saov_M00621  Glycine cleavage system [PATH:saov00630]
saov_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:saov00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces aureoverticillatus [GN:saov]
Gene
G3H79_37620  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
G3H79_06665  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
G3H79_16575  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
G3H79_37615  malate synthase A [KO:K01638] [EC:2.3.3.9]
G3H79_06445  malate synthase A [KO:K01638] [EC:2.3.3.9]
G3H79_13955  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
G3H79_24375  citrate synthase [KO:K01647] [EC:2.3.3.1]
G3H79_37765  bifunctional 2-methylcitrate synthase/citrate synthase [KO:K01647] [EC:2.3.3.1]
G3H79_08505  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
G3H79_08510  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
G3H79_20735  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
G3H79_07940  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
G3H79_26270  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
G3H79_34990  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
G3H79_04770  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G3H79_05005  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G3H79_11005  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G3H79_22065  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
G3H79_11010  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
G3H79_06005  protein meaA [KO:K14447] [EC:5.4.99.63]
G3H79_13180  biotin/lipoyl-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
G3H79_13160  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
G3H79_13165  acyl-CoA carboxylase subunit epsilon [KO:K27095]
G3H79_32600  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
G3H79_32605  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
G3H79_23180  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
G3H79_06635  catalase [KO:K03781] [EC:1.11.1.6]
G3H79_11815  catalase [KO:K03781] [EC:1.11.1.6]
G3H79_12580  catalase [KO:K03781] [EC:1.11.1.6]
G3H79_20455  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
G3H79_33630  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
G3H79_26850  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
G3H79_26970  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
G3H79_27055  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
G3H79_30650  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
G3H79_10470  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G3H79_11190  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G3H79_13750  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
G3H79_31970  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
G3H79_10460  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
G3H79_27155  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G3H79_33075  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
G3H79_10465  gcvH; glycine cleavage system protein GcvH [KO:K02437]
G3H79_06650  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
G3H79_06625  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
G3H79_06630  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
G3H79_27335  glycerate kinase [KO:K00865] [EC:2.7.1.165]
G3H79_06035  glycerate kinase [KO:K00865] [EC:2.7.1.165]
G3H79_02105  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
G3H79_26110  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
G3H79_26475  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
G3H79_11450  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
G3H79_30235  formate dehydrogenase [KO:K00127]
G3H79_20845  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
G3H79_05265  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
saov00010  Glycolysis / Gluconeogenesis
saov00020  Citrate cycle (TCA cycle)
saov00030  Pentose phosphate pathway
saov00053  Ascorbate and aldarate metabolism
saov00071  Fatty acid degradation
saov00230  Purine metabolism
saov00250  Alanine, aspartate and glutamate metabolism
saov00260  Glycine, serine and threonine metabolism
saov00620  Pyruvate metabolism
saov00710  Carbon fixation by Calvin cycle
saov00750  Vitamin B6 metabolism
saov00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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