KEGG   PATHWAY: schf00630
Entry
schf00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces chromofuscus
Class
Metabolism; Carbohydrate metabolism
Pathway map
schf00630  Glyoxylate and dicarboxylate metabolism
schf00630

Module
schf_M00621  Glycine cleavage system [PATH:schf00630]
schf_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:schf00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces chromofuscus [GN:schf]
Gene
IPT68_01410  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
IPT68_19935  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
IPT68_29775  malate synthase A [KO:K01638] [EC:2.3.3.9]
IPT68_22085  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
IPT68_27645  citrate synthase [KO:K01647] [EC:2.3.3.1]
IPT68_27650  citrate synthase [KO:K01647] [EC:2.3.3.1]
IPT68_13325  citrate synthase [KO:K01647] [EC:2.3.3.1]
IPT68_16195  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
IPT68_28175  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
IPT68_25590  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IPT68_31555  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IPT68_14945  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
IPT68_25585  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
IPT68_30320  protein meaA [KO:K14447] [EC:5.4.99.63]
IPT68_15450  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
IPT68_22710  biotin/lipoyl-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
IPT68_22740  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
IPT68_22735  acyl-CoA carboxylase subunit epsilon [KO:K27095]
IPT68_28420  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
IPT68_28425  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
IPT68_22415  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
IPT68_14180  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
IPT68_24005  catalase [KO:K03781] [EC:1.11.1.6]
IPT68_02290  catalase [KO:K03781] [EC:1.11.1.6]
IPT68_16400  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
IPT68_31915  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
IPT68_07130  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
IPT68_10415  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
IPT68_10470  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
IPT68_10620  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
IPT68_25435  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
IPT68_25940  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
IPT68_22145  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
IPT68_05945  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
IPT68_25950  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
IPT68_30195  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IPT68_10270  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
IPT68_25945  gcvH; glycine cleavage system protein GcvH [KO:K02437]
IPT68_29555  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
IPT68_29575  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
IPT68_29570  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
IPT68_30285  glycerate kinase [KO:K00865] [EC:2.7.1.165]
IPT68_11020  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
IPT68_24365  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
IPT68_01300  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
IPT68_03970  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
IPT68_03965  dehydrogenase [KO:K00123] [EC:1.17.1.9]
IPT68_01295  NAD(P)H-dependent oxidoreductase subunit E [KO:K00124]
IPT68_03955  4Fe-4S dicluster domain-containing protein [KO:K00124]
IPT68_07570  cytochrome b/b6 domain-containing protein [KO:K00127]
IPT68_32270  cytochrome b/b6 domain-containing protein [KO:K00127]
IPT68_16140  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
IPT68_30850  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
schf00010  Glycolysis / Gluconeogenesis
schf00020  Citrate cycle (TCA cycle)
schf00030  Pentose phosphate pathway
schf00053  Ascorbate and aldarate metabolism
schf00071  Fatty acid degradation
schf00230  Purine metabolism
schf00250  Alanine, aspartate and glutamate metabolism
schf00260  Glycine, serine and threonine metabolism
schf00620  Pyruvate metabolism
schf00710  Carbon fixation by Calvin cycle
schf00750  Vitamin B6 metabolism
schf00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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