KEGG   PATHWAY: sdv00630
Entry
sdv00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces davaonensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
sdv00630  Glyoxylate and dicarboxylate metabolism
sdv00630

Module
sdv_M00012  Glyoxylate cycle [PATH:sdv00630]
sdv_M00621  Glycine cleavage system [PATH:sdv00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces davaonensis [GN:sdv]
Gene
BN159_0717  icl; Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BN159_2117  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BN159_1371  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BN159_4133  acsA; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BN159_0718  aceB1; Malate synthase [KO:K01638] [EC:2.3.3.9]
BN159_2072  aceB3; Malate synthase [KO:K01638] [EC:2.3.3.9]
BN159_3592  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BN159_2616  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BN159_2617  citrate synthase-like protein [KO:K01647] [EC:2.3.3.1]
BN159_5555  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
BN159_4954  citA; Putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
BN159_2431  acnA; Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
BN159_1690  fadA1; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_1372  thlA1; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_3016  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_5199  thlA3; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_6433  pcaF3; Beta-ketoadipyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
BN159_8183  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_6032  phaA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN159_3017  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
BN159_1953  meaA; Protein meaA [KO:K14447] [EC:5.4.99.63]
BN159_2136  pccB1; Propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BN159_3476  bccA; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
BN159_3471  pccB7; Propionyl-CoA carboxylase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
BN159_3472  putative secreted protein [KO:K27095]
BN159_3530  bhbA; Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
BN159_5364  oxidoreductase, FAD-binding protein [KO:K00104] [EC:1.1.99.14]
BN159_2105  katA; Catalase [KO:K03781] [EC:1.11.1.6]
BN159_3176  bca; Bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
BN159_4906  hydrolase [KO:K01091] [EC:3.1.3.18]
BN159_7790  hydrolase [KO:K01091] [EC:3.1.3.18]
BN159_1564  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN159_6185  glnA1; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
BN159_6216  glnII; Glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
BN159_6229  glnA3; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN159_6970  glutamine synthetase, type III [KO:K01915] [EC:6.3.1.2]
BN159_3574  glyA5; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BN159_2936  glyA1; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BN159_3047  glyA3; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BN159_4095  hypothetical protein [KO:K00600] [EC:2.1.2.1]
BN159_7216  gcvP; Glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
BN159_2934  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BN159_1004  lpd; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN159_6251  Dihydrolipoyl dehydrogenase 1 [KO:K00382] [EC:1.8.1.4]
BN159_2935  gcvH; Glycine cleavage system H protein [KO:K02437]
BN159_2107  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BN159_2103  hypothetical protein [KO:K01816] [EC:5.3.1.22]
BN159_2104  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BN159_1961  glxK; Glycerate kinase [KO:K00865] [EC:2.7.1.165]
BN159_6100  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BN159_3096  kgd; 2-oxoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
BN159_0219  hypothetical protein [KO:K00127]
BN159_6891  hypothetical protein [KO:K00127]
BN159_4968  purU1; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BN159_7400  purU3; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BN159_1847  frc; Formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sdv00010  Glycolysis / Gluconeogenesis
sdv00020  Citrate cycle (TCA cycle)
sdv00030  Pentose phosphate pathway
sdv00053  Ascorbate and aldarate metabolism
sdv00071  Fatty acid degradation
sdv00230  Purine metabolism
sdv00250  Alanine, aspartate and glutamate metabolism
sdv00260  Glycine, serine and threonine metabolism
sdv00620  Pyruvate metabolism
sdv00710  Carbon fixation by Calvin cycle
sdv00750  Vitamin B6 metabolism
sdv00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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