KEGG   PATHWAY: seub04148
Entry
seub04148                   Pathway                                
Name
Efferocytosis - Saccharomyces eubayanus
Class
Cellular Processes; Transport and catabolism
Pathway map
seub04148  Efferocytosis
seub04148

Organism
Saccharomyces eubayanus [GN:seub]
Gene
DI49_3771  LCB5-like protein [KO:K04718] [EC:2.7.1.91]
DI49_5004  LCB4-like protein [KO:K04718] [EC:2.7.1.91]
DI49_2003  KSS1-like protein [KO:K04371] [EC:2.7.11.24]
DI49_0164  FUS3-like protein [KO:K04371] [EC:2.7.11.24]
DI49_3638  HOG1-like protein [KO:K04441] [EC:2.7.11.24]
DI49_1300  PPS1-like protein [KO:K04459] [EC:3.1.3.16 3.1.3.48]
DI49_0035  DRS2-like protein [KO:K14802] [EC:7.6.2.1]
DI49_4428  LEM3-like protein [KO:K26935]
DI49_0836  CDC50-like protein [KO:K26935]
DI49_3386  YPT52-like protein [KO:K07889]
DI49_4927  VPS21-like protein [KO:K07889]
DI49_0658  VPS3-like protein [KO:K20177]
DI49_0057  VPS8-like protein [KO:K20178]
DI49_4315  PEP5-like protein [KO:K20179]
DI49_5413  VPS16-like protein [KO:K20180]
DI49_3673  PEP3-like protein [KO:K20181]
DI49_3896  VPS33-like protein [KO:K20182]
DI49_0989  VAM6-like protein [KO:K20183]
DI49_0277  VPS41-like protein [KO:K20184]
DI49_4088  YPT7-like protein [KO:K07897]
DI49_2313  hypothetical protein [KO:K23678]
DI49_0530  hypothetical protein [KO:K23678]
DI49_1175  RTC2-like protein [KO:K23678]
DI49_5352  CAR1-like protein [KO:K01476] [EC:3.5.3.1]
DI49_3198  SPE1-like protein [KO:K01581] [EC:4.1.1.17]
DI49_1368  RIP1-like protein [KO:K00411] [EC:7.1.1.8]
DI49_3239  TGL1-like protein [KO:K01052] [EC:3.1.1.13]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
seub00010  Glycolysis / Gluconeogenesis
seub04145  Phagosome
KO pathway
ko04148   
LinkDB

DBGET integrated database retrieval system