KEGG   PATHWAY: sfy00630
Entry
sfy00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces fagopyri
Class
Metabolism; Carbohydrate metabolism
Pathway map
sfy00630  Glyoxylate and dicarboxylate metabolism
sfy00630

Module
sfy_M00621  Glycine cleavage system [PATH:sfy00630]
sfy_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sfy00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces fagopyri [GN:sfy]
Gene
GFH48_04645  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GFH48_10385  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GFH48_19210  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GFH48_10230  malate synthase A [KO:K01638] [EC:2.3.3.9]
GFH48_16865  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GFH48_03140  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
GFH48_11645  citrate synthase [KO:K01647] [EC:2.3.3.1]
GFH48_11650  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
GFH48_22875  citrate synthase [KO:K01647] [EC:2.3.3.1]
GFH48_25935  citrate synthase [KO:K01647] [EC:2.3.3.1]
GFH48_11265  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
GFH48_04700  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GFH48_08255  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GFH48_13970  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GFH48_24095  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GFH48_28200  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
GFH48_29865  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GFH48_37085  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
GFH48_13975  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GFH48_09630  protein meaA [KO:K14447] [EC:5.4.99.63]
GFH48_16280  biotin/lipoyl-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
GFH48_20465  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
GFH48_16250  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
GFH48_16255  acyl-CoA carboxylase subunit epsilon [KO:K27095]
GFH48_38080  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GFH48_38085  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GFH48_16595  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
GFH48_25005  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GFH48_15015  catalase [KO:K03781] [EC:1.11.1.6]
GFH48_15720  catalase [KO:K03781] [EC:1.11.1.6]
GFH48_22665  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GFH48_25355  HAD hydrolase-like protein [KO:K01091] [EC:3.1.3.18]
GFH48_28775  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GFH48_28915  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GFH48_28960  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GFH48_32370  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GFH48_13615  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GFH48_14125  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GFH48_16785  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
GFH48_33740  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
GFH48_13605  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GFH48_05975  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GFH48_29050  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GFH48_03695  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GFH48_13610  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GFH48_10370  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
GFH48_10345  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
GFH48_10350  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GFH48_09690  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GFH48_00490  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GFH48_06805  aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GFH48_28390  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GFH48_14630  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
GFH48_19815  NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
GFH48_01940  formate dehydrogenase [KO:K00127]
GFH48_31910  formate dehydrogenase [KO:K00127]
GFH48_22945  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GFH48_36375  AMP-binding protein [KO:K22133] [EC:6.2.1.8]
GFH48_09200  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sfy00010  Glycolysis / Gluconeogenesis
sfy00020  Citrate cycle (TCA cycle)
sfy00030  Pentose phosphate pathway
sfy00053  Ascorbate and aldarate metabolism
sfy00071  Fatty acid degradation
sfy00230  Purine metabolism
sfy00250  Alanine, aspartate and glutamate metabolism
sfy00260  Glycine, serine and threonine metabolism
sfy00620  Pyruvate metabolism
sfy00710  Carbon fixation by Calvin cycle
sfy00750  Vitamin B6 metabolism
sfy00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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