KEGG   PATHWAY: smel00630
Entry
smel00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sinorhizobium meliloti 2011
Class
Metabolism; Carbohydrate metabolism
Pathway map
smel00630  Glyoxylate and dicarboxylate metabolism
smel00630

Module
smel_M00012  Glyoxylate cycle [PATH:smel00630]
smel_M00621  Glycine cleavage system [PATH:smel00630]
smel_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:smel00630]
Other DBs
GO: 0046487 0043648
Organism
Sinorhizobium meliloti 2011 [GN:smel]
Gene
SM2011_c00768  aceA; putative isocitrate lyase [KO:K01637] [EC:4.1.3.1]
SM2011_c00741  acsA3; Putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SM2011_c04093  acsA1; putative acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SM2011_c02581  glcB; putative malate synthase G [KO:K01638] [EC:2.3.3.9]
SM2011_c02479  mdh; putative malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SM2011_c02087  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
SM2011_c03846  acnA; putative aconitate hydratase [KO:K01681] [EC:4.2.1.3]
SM2011_c03879  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SM2011_c02228  fadA; Putative acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
SM2011_c00966  Putative acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
SM2011_a1450  Thiolase [KO:K00626] [EC:2.3.1.9]
SM2011_c00262  Putative 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SM2011_c03878  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
SM2011_c01930  Putative methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
SM2011_b20756  pccA; Putative propionyl-CoA carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
SM2011_b20755  pccB; Putative propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SM2011_b20757  bhbA; Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
SM2011_c00832  glcD; putative glycolate oxidase subunit [KO:K00104] [EC:1.1.99.14]
SM2011_c00833  glcE; putative glycolate oxidase subunit [KO:K11472] [EC:1.1.99.14]
SM2011_c00926  glcF; putative glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
SM2011_c00819  katA; Catalase [KO:K03781] [EC:1.11.1.6]
SM2011_b20007  katC; Catalase [KO:K03781] [EC:1.11.1.6]
SM2011_c02849  gyaR; putative glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
SM2011_c02828  NAD-dependent dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
SM2011_a1838  dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
SM2011_c00893  putative phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM2011_c01276  gph2; Putative phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM2011_c00151  gph1; putative phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM2011_b20198  cbbL; Putative ribulose-1,5-bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
SM2011_b20197  cbbS; Putative ribulose-1,5-bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
SM2011_a2139  sgaA; SgaA serine-glyoxylate aminotransferase (SGAT) [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
SM2011_a1495  Aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
SM2011_c00762  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM2011_c00948  glnA; Glutamine synthetase I [KO:K01915] [EC:6.3.1.2]
SM2011_c01973  puuA; Putative Gamma-glutamylputrescine synthetase [KO:K01915] [EC:6.3.1.2]
SM2011_c01594  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM2011_c02352  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM2011_b20745  glnII; Glutamate-ammonia ligase [KO:K01915] [EC:6.3.1.2]
SM2011_c01770  glyA1; putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SM2011_a2135  glyA2; GlyA2 serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SM2011_c02049  gcvP; putative glycine dehydrogenase decarboxylating protein [KO:K00281] [EC:1.4.4.2]
SM2011_a2145  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SM2011_c02047  gcvT; putative aminomethyltransferase (glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
SM2011_c04153  Putative aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SM2011_c04148  Putative aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SM2011_c01035  lpdA1; putative dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex) protein [KO:K00382] [EC:1.8.1.4]
SM2011_c03204  lpdA3; putative dihydrolipoamide dehydrogenase (E3 component of branched-chain alpha-keto acid dehydrogenase complex) protein [KO:K00382] [EC:1.8.1.4]
SM2011_c02487  lpdA2; putative dihydrolipoamide dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) transmembrane protein [KO:K00382] [EC:1.8.1.4]
SM2011_c02048  gcvH; putative glycine cleavage system H [KO:K02437]
SM2011_b20681  gcl; Putative glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SM2011_b20680  hyi; Putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
SM2011_b20679  glxR; putative 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
SM2011_a0237  dehydrogenase [KO:K00042] [EC:1.1.1.60]
SM2011_a0516  dehydrogenase [KO:K00042] [EC:1.1.1.60]
SM2011_b20678  ttuD2; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
SM2011_c04389  ttuD1; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
SM2011_a1406  ttuD3; TtuD3 hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
SM2011_a1846  dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
SM2011_c02043  eda1; putative KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SM2011_c03153  eda2; putative KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SM2011_a0478  Putative formate dehydrogenase,NAD-dependent [KO:K00122] [EC:1.17.1.9]
SM2011_c03086  fdsD; Putative NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
SM2011_c04444  fdsA; putative NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
SM2011_a6001  hypothetical protein [KO:K00123] [EC:1.17.1.9]
SM2011_a0002  fdoG; formate dehydrogenase,major subunit (formate dehydrogenase alpha subunit) [KO:K00123] [EC:1.17.1.9]
SM2011_c02525  fdsB; Putative NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
SM2011_a0005  fdoH; formate dehydrogenase-O,iron-sulfur subunit [KO:K00124]
SM2011_c02524  fdsG; Putative NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
SM2011_a0007  fdoI; formate dehydrogenase,cytochrome B556 (FDO) subunit [KO:K00127]
SM2011_a0259  hypothetical protein [KO:K01432] [EC:3.5.1.9]
SM2011_a2141  purU3; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SM2011_c04154  purU2; putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SM2011_c03205  purU1; Putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SM2011_b21164  hutG; Putative formiminoglutamase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
smel00010  Glycolysis / Gluconeogenesis
smel00020  Citrate cycle (TCA cycle)
smel00030  Pentose phosphate pathway
smel00053  Ascorbate and aldarate metabolism
smel00071  Fatty acid degradation
smel00230  Purine metabolism
smel00250  Alanine, aspartate and glutamate metabolism
smel00260  Glycine, serine and threonine metabolism
smel00620  Pyruvate metabolism
smel00710  Carbon fixation by Calvin cycle
smel00750  Vitamin B6 metabolism
smel00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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