KEGG   PATHWAY: smx00630
Entry
smx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sinorhizobium meliloti SM11
Class
Metabolism; Carbohydrate metabolism
Pathway map
smx00630  Glyoxylate and dicarboxylate metabolism
smx00630

Module
smx_M00012  Glyoxylate cycle [PATH:smx00630]
smx_M00621  Glycine cleavage system [PATH:smx00630]
smx_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:smx00630]
Other DBs
GO: 0046487 0043648
Organism
Sinorhizobium meliloti SM11 [GN:smx]
Gene
SM11_chr0359  aceA; Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
SM11_chr2791  acsA3; probabable acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SM11_chr3451  acsA1; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SM11_chr3527  glcB; probabable malate synthase g protein [KO:K01638] [EC:2.3.3.9]
SM11_chr3235  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SM11_chr2058  gltA; citrate synthase protein [KO:K01647] [EC:2.3.3.1]
SM11_chr3357  acnA; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
SM11_chr0160  fadA; probabable acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SM11_chr0541  putative acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
SM11_pC0858  Thiolase [KO:K00626] [EC:2.3.1.9]
SM11_chr1715  acaB; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SM11_pC1218  fadA5; thiolase [KO:K00626] [EC:2.3.1.9]
SM11_chr3390  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SM11_chr3389  phbB; PhbB [KO:K00023] [EC:1.1.1.36]
SM11_chr2292  hypothetical protein [KO:K05606] [EC:5.1.99.1]
SM11_pD0169  pccA; putative propionyl-CoA carboxylase alpha chain protein [KO:K01965] [EC:6.4.1.3]
SM11_pD0170  pccB; putative propionyl-CoA carboxylase beta chain protein [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SM11_pD0168  bhbA; methylmalonyl-CoA mutase protein [KO:K01847] [EC:5.4.99.2]
SM11_chr0431  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
SM11_chr0432  glcE; glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
SM11_chr0433  glcF; glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
SM11_chr0418  katA; KatA [KO:K03781] [EC:1.11.1.6]
SM11_pD0040  katC; KatC [KO:K03781] [EC:1.11.1.6]
SM11_chr3646  gyaR; probabable glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
SM11_chr3626  Dehydrogenase, NAD-dependent [KO:K12972] [EC:1.1.1.79 1.1.1.81]
SM11_pC0621  dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
SM11_chr0466  probabable phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM11_chr2184  gph2; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM11_chr1542  gph1; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SM11_pD1412  cbbL; putative ribulose-1,5-bisphosphate carboxylase large subunit protein [KO:K01601] [EC:4.1.1.39]
SM11_pD1413  cbbS; putative ribulose-1,5-bisphosphate carboxylase small subunit protein [KO:K01602] [EC:4.1.1.39]
SM11_pC0836  Aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
SM11_chr0345  glnA1; glutamine synthetase I [KO:K01915] [EC:6.3.1.2]
SM11_pD0180  glnII; putative glutatmine synthetase II protein [KO:K01915] [EC:6.3.1.2]
SM11_chr1046  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM11_chr1768  glnA2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM11_chr2733  glnA3; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SM11_chr2661  puuA; putative gamma-glutamylputrescine synthetase [KO:K01915] [EC:6.3.1.2]
SM11_chr3561  glnT; glutamine synthetase III protein [KO:K01915] [EC:6.3.1.2]
SM11_chr2456  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SM11_chr2019  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SM11_chr2017  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
SM11_chr3570  putative aminomethyltransferase protein [KO:K00605] [EC:2.1.2.10]
SM11_chr3575  putative aminomethyltransferase protein [KO:K00605] [EC:2.1.2.10]
SM11_chr3227  lpdA2; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SM11_chr2118  lpdA1; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SM11_chr3107  lpdA3; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SM11_chr2018  gcvH; glycine cleavage system protein H [KO:K02437]
SM11_pD0231  gcl; putative glyoxylate carboligase protein [KO:K01608] [EC:4.1.1.47]
SM11_pD0232  hyi; putative hydroxypyruvate isomerase protein [KO:K01816] [EC:5.3.1.22]
SM11_pC1527  dehydrogenase [KO:K00042] [EC:1.1.1.60]
SM11_pC1612  dehydrogenase [KO:K00042] [EC:1.1.1.60]
SM11_pD0233  glxR; probabable tartronic semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
SM11_pD0234  ttuD2; putative hydroxypyruvate reductase protein [KO:K11529] [EC:2.7.1.165]
SM11_chr3417  ttuD1; putative hydroxypyruvate reductase protein [KO:K11529] [EC:2.7.1.165]
SM11_pC0883  ttuD3; TtuD3 hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
SM11_pC0617  dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
SM11_chr2709  eda1; probabable khg/kdpg aldolase protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SM11_chr3053  eda2; probabable khg/kdpg aldolase protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SM11_pC1434  Dehydrogenase, NAD-dependent [KO:K00122] [EC:1.17.1.9]
SM11_chr3186  fdsD; NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
SM11_chr3188  fdsA; NAD-dependent formate dehydrogenase alpha subunit protein [KO:K00123] [EC:1.17.1.9]
SM11_pC1759  fdoG-2; formate dehydrogenase, major subunit (formate dehydrogenase alpha subunit) [KO:K00123] [EC:1.17.1.9]
SM11_pC1760  fdoG-1; formate dehydrogenase, major subunit (formate dehydrogenase alpha subunit) [KO:K00123] [EC:1.17.1.9]
SM11_chr3189  fdsB; putative NAD-dependent formate dehydrogenase beta subunit protein [KO:K00124]
SM11_pC1758  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
SM11_chr3190  fdsG; NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
SM11_pC1757  fdoI; formate dehydrogenase, gamma subunit [KO:K00127]
SM11_pC1601  conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
SM11_chr3108  purU1; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SM11_chr3569  purU2; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SM11_pD0764  hutG; putative formiminoglutamase protein [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
smx00010  Glycolysis / Gluconeogenesis
smx00020  Citrate cycle (TCA cycle)
smx00030  Pentose phosphate pathway
smx00053  Ascorbate and aldarate metabolism
smx00071  Fatty acid degradation
smx00230  Purine metabolism
smx00250  Alanine, aspartate and glutamate metabolism
smx00260  Glycine, serine and threonine metabolism
smx00620  Pyruvate metabolism
smx00710  Carbon fixation by Calvin cycle
smx00750  Vitamin B6 metabolism
smx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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