KEGG   PATHWAY: svr00630
Entry
svr00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces viridifaciens
Class
Metabolism; Carbohydrate metabolism
Pathway map
svr00630  Glyoxylate and dicarboxylate metabolism
svr00630

Module
svr_M00621  Glycine cleavage system [PATH:svr00630]
svr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:svr00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces viridifaciens [GN:svr]
Gene
CP971_17875  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CP971_05940  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
CP971_20150  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CP971_10205  citrate synthase [KO:K01647] [EC:2.3.3.1]
CP971_14305  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
CP971_22450  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
CP971_11795  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP971_13340  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP971_25985  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP971_11800  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CP971_08935  protein meaA [KO:K14447] [EC:5.4.99.63]
CP971_20405  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
CP971_20425  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
CP971_20420  acyl-CoA carboxylase subunit epsilon [KO:K27095]
CP971_28395  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP971_28400  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP971_20240  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
CP971_17135  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
CP971_05870  catalase [KO:K03781] [EC:1.11.1.6]
CP971_12485  catalase [KO:K03781] [EC:1.11.1.6]
CP971_28925  catalase HPII [KO:K03781] [EC:1.11.1.6]
CP971_14195  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
CP971_14415  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CP971_28240  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CP971_08915  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP971_09085  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP971_24035  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CP971_24140  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CP971_26715  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP971_33700  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP971_05230  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP971_11560  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP971_11945  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP971_29495  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP971_04385  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CP971_11550  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
CP971_31625  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP971_24220  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP971_11555  gcvH; glycine cleavage system protein GcvH [KO:K02437]
CP971_19170  gcvH; glycine cleavage system protein GcvH [KO:K02437]
CP971_31040  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CP971_05895  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CP971_05890  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CP971_05885  glycerate kinase [KO:K00865] [EC:2.7.1.165]
CP971_33095  aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CP971_04255  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CP971_12165  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
CP971_30060  formate dehydrogenase [KO:K00127]
CP971_14145  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
svr00010  Glycolysis / Gluconeogenesis
svr00020  Citrate cycle (TCA cycle)
svr00030  Pentose phosphate pathway
svr00053  Ascorbate and aldarate metabolism
svr00071  Fatty acid degradation
svr00230  Purine metabolism
svr00250  Alanine, aspartate and glutamate metabolism
svr00260  Glycine, serine and threonine metabolism
svr00620  Pyruvate metabolism
svr00710  Carbon fixation by Calvin cycle
svr00750  Vitamin B6 metabolism
svr00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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