KEGG   PATHWAY: syan00630
Entry
syan00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces yangpuensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
syan00630  Glyoxylate and dicarboxylate metabolism
syan00630

Module
syan_M00621  Glycine cleavage system [PATH:syan00630]
syan_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:syan00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces yangpuensis [GN:syan]
Gene
NRK68_27620  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
NRK68_01760  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NRK68_18340  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NRK68_27715  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
NRK68_20745  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
NRK68_25700  citrate synthase [KO:K01647] [EC:2.3.3.1]
NRK68_25705  citrate synthase [KO:K01647] [EC:2.3.3.1]
NRK68_12215  citrate synthase [KO:K01647] [EC:2.3.3.1]
NRK68_14890  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
NRK68_26620  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
NRK68_23625  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NRK68_28550  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NRK68_03405  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
NRK68_09045  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NRK68_10690  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
NRK68_13620  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NRK68_23620  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NRK68_28080  protein meaA [KO:K14447] [EC:5.4.99.63]
NRK68_21145  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
NRK68_21170  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
NRK68_21165  acyl-CoA carboxylase subunit epsilon [KO:K27095]
NRK68_26240  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
NRK68_26245  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
NRK68_20915  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
NRK68_35105  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
NRK68_35100  cobalamin-dependent protein [KO:K01846] [EC:5.4.99.1]
NRK68_12945  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
NRK68_27655  catalase [KO:K03781] [EC:1.11.1.6]
NRK68_30390  catalase [KO:K03781] [EC:1.11.1.6]
NRK68_22660  catalase [KO:K03781] [EC:1.11.1.6]
NRK68_15115  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
NRK68_07155  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NRK68_09975  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NRK68_10070  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
NRK68_10270  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NRK68_23465  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NRK68_23960  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NRK68_04300  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NRK68_20795  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NRK68_05790  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NRK68_23970  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
NRK68_09935  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NRK68_23965  gcvH; glycine cleavage system protein GcvH [KO:K02437]
NRK68_27635  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
NRK68_27665  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
NRK68_27660  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
NRK68_28020  glycerate kinase [KO:K00865] [EC:2.7.1.165]
NRK68_32045  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
NRK68_23105  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
NRK68_14820  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
syan00010  Glycolysis / Gluconeogenesis
syan00020  Citrate cycle (TCA cycle)
syan00030  Pentose phosphate pathway
syan00053  Ascorbate and aldarate metabolism
syan00071  Fatty acid degradation
syan00230  Purine metabolism
syan00250  Alanine, aspartate and glutamate metabolism
syan00260  Glycine, serine and threonine metabolism
syan00620  Pyruvate metabolism
syan00710  Carbon fixation by Calvin cycle
syan00750  Vitamin B6 metabolism
syan00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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