KEGG   PATHWAY: ttl00630
Entry
ttl00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thermus thermophilus JL-18
Class
Metabolism; Carbohydrate metabolism
Pathway map
ttl00630  Glyoxylate and dicarboxylate metabolism
ttl00630

Module
ttl_M00012  Glyoxylate cycle [PATH:ttl00630]
ttl_M00621  Glycine cleavage system [PATH:ttl00630]
Other DBs
GO: 0046487 0043648
Organism
Thermus thermophilus JL-18 [GN:ttl]
Gene
TtJL18_1934  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
TtJL18_0798  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
TtJL18_0799  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
TtJL18_0800  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
TtJL18_0764  acyl-CoA synthetase/AMP-acid ligase [KO:K01895] [EC:6.2.1.1]
TtJL18_1570  malate synthase A [KO:K01638] [EC:2.3.3.9]
TtJL18_1540  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
TtJL18_0706  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
TtJL18_1321  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
TtJL18_1516  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
TtJL18_1371  acyl dehydratase [KO:K17865] [EC:4.2.1.55]
TtJL18_1689  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
TtJL18_1021  methylmalonyl-CoA mutase family protein [KO:K01849] [EC:5.4.99.2]
TtJL18_0802  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
TtJL18_1020  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
TtJL18_1254  FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
TtJL18_1571  FAD/FMN-dependent dehydrogenase [KO:K00104] [EC:1.1.99.14]
TtJL18_1572  FAD/FMN-dependent dehydrogenase [KO:K11472] [EC:1.1.99.14]
TtJL18_1573  Fe-S oxidoreductase [KO:K11473] [EC:1.1.99.14]
TtJL18_1266  lactate dehydrogenase-like oxidoreductase [KO:K00015] [EC:1.1.1.26]
TtJL18_0233  serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
TtJL18_0719  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
TtJL18_0518  glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
TtJL18_1551  glycine cleavage system protein P [KO:K00282] [EC:1.4.4.2]
TtJL18_1550  glycine cleavage system protein P [KO:K00283] [EC:1.4.4.2]
TtJL18_1553  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
TtJL18_0169  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
TtJL18_0102  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
TtJL18_1552  glycine cleavage system H protein [KO:K02437]
TtJL18_1575  putative glycerate kinase [KO:K11529] [EC:2.7.1.165]
TtJL18_2245  Entner-Doudoroff aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
TtJL18_1311  dihydrodipicolinate synthase/N-acetylneuraminate lyase [KO:K18123] [EC:4.1.3.16]
TtJL18_0727  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ttl00010  Glycolysis / Gluconeogenesis
ttl00020  Citrate cycle (TCA cycle)
ttl00030  Pentose phosphate pathway
ttl00071  Fatty acid degradation
ttl00230  Purine metabolism
ttl00250  Alanine, aspartate and glutamate metabolism
ttl00260  Glycine, serine and threonine metabolism
ttl00620  Pyruvate metabolism
ttl00710  Carbon fixation by Calvin cycle
ttl00750  Vitamin B6 metabolism
ttl00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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