Entry Name ABC transporters - Yersinia rohdei
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Other DBs Organism Gene CH64_1081 potH; putrescine transport system permease protein PotH [KO:K11075 ]
CH64_11 mglB; D-galactose-binding periplasmic protein [KO:K10540 ]
CH64_1134 yejB; inner membrane ABC transporter permease protein yejB [KO:K13894 ]
CH64_1135 yejE; inner membrane ABC transporter permease protein yejE [KO:K13895 ]
CH64_1223 hisM; histidine transport system permease protein hisM [KO:K10015 ]
CH64_1423 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
CH64_1643 metN; D-methionine ABC transporter, ATP-binding protein [KO:K02071 ]
CH64_1644 metI; D-methionine transport system permease protein metI [KO:K02072 ]
CH64_2185 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
CH64_2257 yhdY; inner membrane amino-acid ABC transporter permease protein yhdY [KO:K09971 ]
CH64_2283 malK; maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
CH64_2500 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
CH64_2576 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
CH64_2577 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
CH64_2578 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
CH64_258 yecS; inner membrane amino-acid ABC transporter permease protein yecS [KO:K10009 ]
CH64_2732 ytfQ; ABC transporter periplasmic-binding protein ytfQ [KO:K23508 ]
CH64_2822 livH; high-affinity branched-chain amino acid transport system permease protein livH [KO:K01997 ]
CH64_2825 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CH64_3261 thiP; thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
CH64_3262 thiB; thiamin/thiamine pyrophosphate ABC transporter, thiamin/thiamine pyrophospate-binding protein [KO:K02064 ]
CH64_3349 fhuB; iron(3+)-hydroxamate import system permease protein fhuB [KO:K23228 ]
CH64_3538 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
CH64_3591 mdlB; multidrug resistance-like ATP-binding protein MdlB [KO:K18890 ]
CH64_3728 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
CH64_3820 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
CH64_407 znuB; high-affinity zinc uptake system membrane protein znuB [KO:K09816 ]
CH64_477 oppB; oligopeptide transport system permease protein oppB [KO:K15581 ]
CH64_478 oppC; oligopeptide transport system permease protein oppC [KO:K15582 ]
CH64_666 sapB; peptide transport system permease protein sapB [KO:K19227 ]
CH64_667 sapC; peptide transport system permease protein sapC [KO:K19228 ]
CH64_669 sapF; peptide transport system ATP-binding protein SapF [KO:K19230 ]
CH64_910 lolE; liporeleasing system, transmembrane protein LolE [KO:K09808 ]
CH64_911 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
CH64_912 lolC; lipo-releasing system transmembrane protein lolC [KO:K09808 ]
CH64_99 cbiQ; cobalt ABC transporter, permease protein CbiQ [KO:K02008 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway
