KEGG   PATHWAY: pfs00564
Entry
pfs00564                    Pathway                                
Name
Glycerophospholipid metabolism - Pseudomonas fluorescens SBW25
Class
Metabolism; Lipid metabolism
Pathway map
pfs00564  Glycerophospholipid metabolism
pfs00564

Module
pfs_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pfs00564]
Other DBs
GO: 0006650
Organism
Pseudomonas fluorescens SBW25 [GN:pfs]
Gene
PFLU_1840  Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) [KO:K00057] [EC:1.1.1.94]
PFLU_1140  glpD; Glycerol-3-phosphate dehydrogenase (EC [KO:K00111] [EC:1.1.5.3]
PFLU_1255  Glycerol-3-phosphate acyltransferase (GPAT) (EC [KO:K00631] [EC:2.3.1.15]
PFLU_5588  Glycerol-3-phosphate acyltransferase (Acyl-PO4 G3P acyltransferase) (Acyl-phosphate--glycerol-3-phosphate acyltransferase) (G3P acyltransferase) (GPAT) (EC (Lysophosphatidic acid synthase) (LPA synthase) [KO:K08591] [EC:2.3.1.275]
PFLU_0008  Putative phospholipid biosynthesis-related acyltransferase [KO:K00655] [EC:2.3.1.51]
PFLU_4658  1-acyl-sn-glycerol-3-phosphate acyltransferase (EC [KO:K00655] [EC:2.3.1.51]
PFLU_1196  dgkA; Diacylglycerol kinase (EC [KO:K00901] [EC:2.7.1.107]
PFLU_1570  Putative glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
PFLU_4789  Putative glycerophosphoryl diester phosphodiesterase (EC [KO:K01126] [EC:3.1.4.46]
PFLU_5443  eutB; Ethanolamine ammonia-lyase heavy chain (EC [KO:K03735] [EC:4.3.1.7]
PFLU_5444  Ethanolamine ammonia-lyase small subunit (EAL small subunit) (EC [KO:K03736] [EC:4.3.1.7]
PFLU_6110  Putative phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
PFLU_1275  cdsA; Phosphatidate cytidylyltransferase (EC [KO:K00981] [EC:2.7.7.41]
PFLU_2780  Phosphatidylcholine synthase (PC synthase) (PCS) (EC (CDP-diglyceride-choline O-phosphatidyltransferase) [KO:K01004] [EC:2.7.8.24]
PFLU_2917  CDP-diacylglycerol-serine O-phosphatidyltransferase (EC [KO:K00998] [EC:2.7.8.8]
PFLU_5217  CDP-diacylglycerol--serine O-phosphatidyltransferase (EC (Phosphatidylserine synthase) [KO:K17103] [EC:2.7.8.8]
PFLU_0505  psd; Phosphatidylserine decarboxylase proenzyme (EC [Cleaved into: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain] [KO:K01613] [EC:4.1.1.65]
PFLU_2191  pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC [KO:K00995] [EC:2.7.8.5]
PFLU_6096  Cardiolipin synthase A (CL synthase) (EC [KO:K06131] [EC:2.7.8.-]
PFLU_5488  Cardiolipin synthase B (CL synthase) (EC [KO:K06131] [EC:2.7.8.-]
PFLU_5974  Putative phospholipase D [KO:K06132] [EC:2.7.8.-]
PFLU_1398  Putative phospholipase [KO:K06131] [EC:2.7.8.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
pfs00010  Glycolysis / Gluconeogenesis
pfs00260  Glycine, serine and threonine metabolism
pfs00561  Glycerolipid metabolism
pfs00562  Inositol phosphate metabolism
pfs00565  Ether lipid metabolism
pfs00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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